Barbera Lisa, Thomas Gillian
Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.
Lancet Oncol. 2008 Jan;9(1):54-60. doi: 10.1016/S1470-2045(07)70409-6.
Venous thromboembolism (VTE) is common in malignant disease and is associated with substantial morbidity and mortality. Recently, VTE has received increased attention as a result of the use of newer drugs, such as erythropoietin-stimulating agents or antiangiogenic drugs, which increase the risk of this condition. Several reviews have been published on VTE in cancer, but none have specifically focused on cervical cancer. In this review, we focus on the incidence of VTE, patient, tumour, and treatment-related risk factors for VTE, and treatment and prevention of VTE in the setting of cervical cancer.
静脉血栓栓塞症(VTE)在恶性疾病中很常见,且与较高的发病率和死亡率相关。最近,由于使用了如促红细胞生成素或抗血管生成药物等新型药物,VTE的风险增加,因此受到了更多关注。关于癌症患者VTE的已有多篇综述发表,但均未专门聚焦于宫颈癌。在本综述中,我们重点关注VTE的发病率、患者、肿瘤以及与治疗相关的VTE危险因素,以及宫颈癌患者VTE的治疗和预防。