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雷洛昔芬对去卵巢大鼠甲状腺形态的影响。

Raloxifene effects on thyroid gland morphology in ovariectomized rats.

作者信息

de Araujo Luiz Felipe Bittencourt, Grozovsky Renata, de Campos Pinheiro Mônica, de Carvalho Jorge José, Vaisman Mário, Carvalho Denise P

机构信息

Laboratório de Fisiologia Endócrina, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.

出版信息

Fertil Steril. 2008 Oct;90(4):1211-4. doi: 10.1016/j.fertnstert.2007.10.046. Epub 2008 Jan 7.

DOI:10.1016/j.fertnstert.2007.10.046
PMID:18178201
Abstract

We aimed to analyze the effects of raloxifene and estrogen on thyroid gland morphology of ovariectomized rats. Raloxifene treatment led to effects similar to those of estrogen on thyroid glands from ovariectomized rats, so that both were able to normalize the changes detected after ovariectomy.

摘要

我们旨在分析雷洛昔芬和雌激素对去卵巢大鼠甲状腺形态的影响。雷洛昔芬治疗对去卵巢大鼠甲状腺产生的作用与雌激素相似,因此二者均能使去卵巢后检测到的变化恢复正常。

相似文献

1
Raloxifene effects on thyroid gland morphology in ovariectomized rats.雷洛昔芬对去卵巢大鼠甲状腺形态的影响。
Fertil Steril. 2008 Oct;90(4):1211-4. doi: 10.1016/j.fertnstert.2007.10.046. Epub 2008 Jan 7.
2
Expressions of vascular endothelial growth factor and nitric oxide synthase III in the thyroid gland of ovariectomized rats are upregulated by estrogen and selective estrogen receptor modulators.雌激素和选择性雌激素受体调节剂可上调去卵巢大鼠甲状腺血管内皮生长因子和一氧化氮合酶 III 的表达。
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Effects of estradiol and raloxifene on arterial thrombosis in ovariectomized mice.雌二醇和雷洛昔芬对去卵巢小鼠动脉血栓形成的影响。
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Effects of two novel selective estrogen receptor modulators, raloxifene, tamoxifen, and ethinyl estradiol on the uterus, vagina and breast in ovariectomized cynomolgus monkeys (Macaca fascicularis).两种新型选择性雌激素受体调节剂(雷洛昔芬、他莫昔芬和炔雌醇)对去卵巢食蟹猴(猕猴)子宫、阴道和乳腺的影响
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