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雷洛昔芬对去卵巢大鼠甲状腺形态的影响。

Raloxifene effects on thyroid gland morphology in ovariectomized rats.

作者信息

de Araujo Luiz Felipe Bittencourt, Grozovsky Renata, de Campos Pinheiro Mônica, de Carvalho Jorge José, Vaisman Mário, Carvalho Denise P

机构信息

Laboratório de Fisiologia Endócrina, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.

出版信息

Fertil Steril. 2008 Oct;90(4):1211-4. doi: 10.1016/j.fertnstert.2007.10.046. Epub 2008 Jan 7.

Abstract

We aimed to analyze the effects of raloxifene and estrogen on thyroid gland morphology of ovariectomized rats. Raloxifene treatment led to effects similar to those of estrogen on thyroid glands from ovariectomized rats, so that both were able to normalize the changes detected after ovariectomy.

摘要

我们旨在分析雷洛昔芬和雌激素对去卵巢大鼠甲状腺形态的影响。雷洛昔芬治疗对去卵巢大鼠甲状腺产生的作用与雌激素相似,因此二者均能使去卵巢后检测到的变化恢复正常。

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