Viget N, Vernier-Massouille G, Salmon-Ceron D, Yazdanpanah Y, Colombel J-F
Service des Maladies Infectieuses et du Voyageur, Centre Hospitalier de Tourcoing, France.
Gut. 2008 Apr;57(4):549-58. doi: 10.1136/gut.2006.114660. Epub 2008 Jan 4.
Because of the increasing use of immunosuppressive and biological drugs, the occurrence of opportunistic infections has become a key safety issue for patients with inflammatory bowel disease (IBD). Consequently, improvement of healthcare workers' knowledge of this domain is urgent. In this review, the preventive measures that would help to reduce the rate of opportunistic infections in patients with IBD are listed, and the management of situations frequently confronting doctors is considered. In the absence of national and international recommendations, the information given here should help doctors to optimise patient outcomes.
由于免疫抑制药物和生物药物的使用日益增加,机会性感染的发生已成为炎症性肠病(IBD)患者的关键安全问题。因此,迫切需要提高医护人员在这一领域的知识水平。在本综述中,列出了有助于降低IBD患者机会性感染发生率的预防措施,并探讨了医生经常面临的情况的管理方法。在缺乏国家和国际建议的情况下,此处提供的信息应有助于医生优化患者的治疗效果。