Berry P A, Hanna F S, Teichtahl A J, Wluka A E, Urquhart D M, Bell R J, Davis S R, Cicuttini F M
Department of Epidemiology and Preventive Medicine, Central and Eastern Clinical School, Monash University, Melbourne, Victoria 3004, Australia.
Osteoarthritis Cartilage. 2008 Aug;16(8):956-60. doi: 10.1016/j.joca.2007.11.011. Epub 2008 Jan 3.
Although vastus medialis and vastus lateralis are important muscular determinants of patellofemoral joint function, it is unclear how these muscles relate to the structure of the patellofemoral joint. The aim of this cross-sectional study was to determine the relationship between the vasti muscles and patella cartilage volume and defects and patella bone volume.
One hundred and seventy-five women, aged 40-67 years, with no knee pain or clinical lower-limb disease had magnetic resonance imaging (MRI) of their dominant knee. The cross-sectional areas of the distal vastus medialis and lateralis were measured 37.5mm superior to the quadriceps tendon insertion at the proximal pole of the patella. Patella cartilage volume and defects and patella bone volume were measured from these images using validated methods.
There was no significant association between the distal vastus medialis cross-sectional area and patella cartilage volume. For every 1mm(2) increase in the distal vastus medialis cross-sectional area, there was an associated increased risk of patella cartilage defects [odds ratio (OR): 1.2; 95% confidence interval (CI) 1.004, 1.5; P=0.05], and an associated increase in patella bone volume (OR: 3.9; 95% CI 2.0, 5.8; P<0.001) after adjustment for potential confounders. There was no significant relationship between vastus lateralis cross-sectional area and measures of patella cartilage or bone.
An increased cross-sectional area of the distal portion of the vastus medialis muscle is associated with an increased risk of patella cartilage defects, and an increase in patella bone volume among healthy women. Although these results need to be confirmed in longitudinal studies, they suggest that an increase in the distal vastus medialis cross-sectional area is associated with structural change at the patellofemoral joint.
虽然股内侧肌和股外侧肌是髌股关节功能的重要肌肉决定因素，但尚不清楚这些肌肉与髌股关节结构之间的关系。本横断面研究的目的是确定股肌与髌骨软骨体积、缺损以及髌骨骨体积之间的关系。
175名年龄在40 - 67岁之间、无膝关节疼痛或临床下肢疾病的女性对其优势膝关节进行了磁共振成像（MRI）检查。在髌骨近端极点处股四头肌腱附着点上方37.5mm处测量股内侧肌和股外侧肌远端的横截面积。使用经过验证的方法从这些图像中测量髌骨软骨体积、缺损以及髌骨骨体积。
股内侧肌远端横截面积与髌骨软骨体积之间无显著关联。在调整潜在混杂因素后，股内侧肌远端横截面积每增加1mm²，髌骨软骨缺损风险增加[比值比（OR）：1.2；95%置信区间（CI）1.004，1.5；P = 0.05]，且髌骨骨体积增加（OR：3.9；95%CI 2.0，5.8；P < 0.001）。股外侧肌横截面积与髌骨软骨或骨的测量指标之间无显著关系。
股内侧肌远端横截面积增加与健康女性髌骨软骨缺损风险增加以及髌骨骨体积增加相关。虽然这些结果需要在纵向研究中得到证实，但它们表明股内侧肌远端横截面积增加与髌股关节结构变化有关。
