• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

体外细胞色素b5与微粒体膜的结合:功能水平和非功能水平

In vitro cytochrome b5 binding to microsomal membranes: functional and non-functional levels.

作者信息

Muna W F, Smuckler E A

出版信息

Res Commun Chem Pathol Pharmacol. 1976 Jun;14(2):287-94.

PMID:181804
Abstract

A comparison of the apparent level of cytochrome binding b5 to liver and kidney microsomes was undertaken comparing values obtained by dithionite vs. NADH reduction. Significant differences both in the extent and specificity of binding to microsomes from liver and kidney were found. These results suggest careful consideration of the apparent binding site availability based on means of reduction is in order.

摘要

对细胞色素b5与肝脏和肾脏微粒体的表观结合水平进行了比较,比较了连二亚硫酸盐还原法和NADH还原法获得的值。发现肝脏和肾脏微粒体在结合程度和特异性方面均存在显著差异。这些结果表明,基于还原方法,有必要仔细考虑表观结合位点的可用性。

相似文献

1
In vitro cytochrome b5 binding to microsomal membranes: functional and non-functional levels.体外细胞色素b5与微粒体膜的结合:功能水平和非功能水平
Res Commun Chem Pathol Pharmacol. 1976 Jun;14(2):287-94.
2
Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.细胞色素b5在重组细胞色素P450 3A4和人肝微粒体对睾酮及硝苯地平氧化反应中的作用。
Arch Biochem Biophys. 1996 Jan 15;325(2):174-82. doi: 10.1006/abbi.1996.0022.
3
The binding of cytochrome b5 to plasma membranes of rat liver: its implication for membrane specificity and biogenesis.细胞色素b5与大鼠肝脏质膜的结合:其对膜特异性和生物发生的意义。
Biochim Biophys Acta. 1980 Apr 24;597(3):564-76. doi: 10.1016/0005-2736(80)90228-x.
4
[Effect of incorporation and removal of cholesterol on the lipid bilayer viscosity and the rate of oxidative reactions in rat liver microsomal membranes].[胆固醇的掺入与去除对大鼠肝微粒体膜脂质双层粘度及氧化反应速率的影响]
Biokhimiia. 1981 Jun;46(6):1109-18.
5
Application of electron-donor properties of glucose oxidase and xanthine oxidase for reduction of microsomal NAD(P)H-dependent electron-transport chains.
Biotechnol Appl Biochem. 1991 Feb;13(1):90-6.
6
1-Hydroxyethyl radical formation during NADPH- and NADH-dependent oxidation of ethanol by human liver microsomes.人肝微粒体在NADPH和NADH依赖的乙醇氧化过程中1-羟乙基自由基的形成。
Mol Pharmacol. 1996 May;49(5):814-21.
7
The involvement of NADH-cytochrome b5 reductase and cytochrome b5 complex in microsomal NADH-cytochrome c reductase activity. Changes in NADH-cytochrome c reductase activity following phenobarbital treatment.NADH - 细胞色素b5还原酶和细胞色素b5复合物在微粒体NADH - 细胞色素c还原酶活性中的作用。苯巴比妥处理后NADH - 细胞色素c还原酶活性的变化。
Acta Biochim Pol. 1974;21(1):61-6.
8
Characterization of gastric cytochrome b5: spectral and immunological identity with liver microsomal cytochrome b5 and immunohistochemical localization in rat fundic mucosa.胃细胞色素b5的特性:与肝微粒体细胞色素b5的光谱和免疫同一性以及在大鼠胃底黏膜中的免疫组织化学定位
Biochem Biophys Res Commun. 1980 Dec 31;97(4):1521-6. doi: 10.1016/s0006-291x(80)80038-6.
9
NADH cytochrome b5 reductase and cytochrome b5 catalyze the microsomal reduction of xenobiotic hydroxylamines and amidoximes in humans.NADH细胞色素b5还原酶和细胞色素b5催化人体内微粒体对外源性羟胺和偕胺肟的还原反应。
J Pharmacol Exp Ther. 2004 Dec;311(3):1171-8. doi: 10.1124/jpet.104.072389. Epub 2004 Aug 9.
10
Influence of two haloalkanes on the redox behavior of hepatic microsomal cytochrome b-5 and its possible relationship to stearate desaturase.两种卤代烷对肝微粒体细胞色素b-5氧化还原行为的影响及其与硬脂酸去饱和酶的可能关系。
Res Commun Chem Pathol Pharmacol. 1981 Dec;34(3):473-84.