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不列颠哥伦比亚省扩大紧急避孕药物可及性的成本与结果建模

Modelling costs and outcomes of expanded availability of emergency contraceptive use in British Columbia.

作者信息

Soon Judith A, Meckley Lisa M, Levine Marc, Marciante Kristin D, Fielding David W, Ensom Mary H H

机构信息

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.

出版信息

Can J Clin Pharmacol. 2007 Fall;14(3):e326-38. Epub 2007 Nov 30.

Abstract

BACKGROUND

Emergency contraception (EC) can potentially reduce unwanted pregnancies and abortions. However, these agents are underused due to lack of awareness and barriers to utilization. While earlier economic evaluations have indicated that use of EC is potentially cost-effective, recent evidence of a lower risk of pregnancy following unprotected intercourse than previously reported suggest prior studies may have over-estimated cost savings.

OBJECTIVES

To model cost savings and pregnancy-related outcomes associated with the policy change authorizing pharmacist provision of EC in British Columbia, and to estimate the costs of initiatives to further women's awareness and utilization of EC that would result.

METHODS

Three decision analytic models were developed evaluating current EC utilization (physician-only), EC utilization following pharmacist provision and potential expanded EC awareness and utilization following a public awareness initiative. Models were developed from the Ministry of Health perspective for 2001 using cost and event data from the Ministry supplemented by data from the literature.

RESULTS

Current EC utilization saved the Ministry $2.20 million (95% CR: $0.15 million, $4.90 million) in medical costs the first year, and incremental savings from pharmacist provision was $0.64 million (95% CR: $0.24 million, $1.28 million). A public awareness initiative costing less than $2.57 million (95% CR: $0.22 million, $5.75 million) annually is potentially cost saving.

CONCLUSIONS

Pharmacist provision of EC was cost saving to the Ministry, even when the estimated risk of pregnancy in the population is less than assumed in previous studies. Increasing EC availability directly from pharmacists and increasing EC awareness have the potential to reduce health care costs.

摘要

背景

紧急避孕(EC)有可能减少意外怀孕和堕胎情况。然而,由于缺乏认识和使用障碍,这些药物未得到充分利用。虽然早期的经济评估表明使用紧急避孕具有潜在的成本效益,但最近有证据表明,无保护性交后怀孕风险低于先前报道,这表明先前的研究可能高估了成本节约情况。

目的

建立模型,模拟与不列颠哥伦比亚省授权药剂师提供紧急避孕的政策变化相关的成本节约和与怀孕相关的结果,并估计为提高女性对紧急避孕的认识和使用率而采取的举措的成本。

方法

开发了三个决策分析模型,分别评估当前紧急避孕的使用情况(仅由医生提供)、药剂师提供紧急避孕后的使用情况以及公众意识倡议后潜在扩大的紧急避孕认识和使用情况。这些模型是从卫生部的角度,使用卫生部的成本和事件数据,并辅以文献数据,针对2001年建立的。

结果

当前紧急避孕的使用在第一年为卫生部节省了220万美元(95%可信区间:15万美元,490万美元)的医疗成本,药剂师提供紧急避孕带来的增量节省为64万美元(95%可信区间:24万美元,128万美元)。一项每年成本低于257万美元(95%可信区间:22万美元,575万美元)的公众意识倡议可能会节省成本。

结论

即使人群中估计的怀孕风险低于先前研究中的假设,药剂师提供紧急避孕对卫生部来说也是节省成本的。直接通过药剂师增加紧急避孕的可及性以及提高对紧急避孕的认识,有可能降低医疗保健成本。

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