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人脱细胞真皮基质加强修补术治疗大型食管旁裂孔疝的长期疗效

Long-term outcome of cruroplasty reinforcement with human acellular dermal matrix in large paraesophageal hiatal hernia.

作者信息

Lee Yong Kwon, James Elaine, Bochkarev Victor, Vitamvas Michelle, Oleynikov Dmitry

机构信息

Department of Surgery, University of Nebraska Medical Center, 983280 Nebraska Medical Center, Omaha, NE 68198-3280, USA.

出版信息

J Gastrointest Surg. 2008 May;12(5):811-5. doi: 10.1007/s11605-007-0463-x. Epub 2008 Jan 8.

Abstract

BACKGROUND

Laparoscopic repair of a large hiatal hernia using simple sutures only for the cruroplasty is associated with a high recurrence rate. The solution was to place synthetic mesh over the cruroplasty thereby decreasing recurrence rates in exchange for complications, such as gastric and esophageal erosions. Our initial report investigated the use of human acellular dermal matrix (AlloDerm) as a more suitable alternative. This study highlights our long-term results>1 year of cruroplasty reinforcement with AlloDerm in the repair of large hiatal hernias.

METHODS AND MATERIAL

This is a retrospective study performed at our university. Between 2005 and 2006, 52 consecutive patients with large hiatal hernias had the cruroplasty site reinforced with AlloDerm. The variables analyzed were age, sex, weight, height, hiatal hernia size, operative time, length of hospital stay, follow-up, and postoperative complications.

RESULTS

The mean for age was 56.7 years, for weight was 87.9 kg, for height 117 cm, for hernia size was 5.75 cm, operative time was 121 min, and for hospital stay was 1.36 days. Complication included pneumothorax, 3 (5.5%); atelectasis, 1 (1.9%); urinary retention, 1 (1.9%); and recurrence, 2 (3.8%).

CONCLUSION

Laparoscopic hiatal hernia repair with reinforcement using human acellular dermal matrix can be performed safely with a short hospital stay and low rate of complications, especially a low rate of recurrence.

摘要

背景

仅使用简单缝合进行腹腔镜下大型食管裂孔疝修补术的食管裂孔成形术复发率较高。解决办法是在食管裂孔成形术上放置合成补片,从而降低复发率,但会换来诸如胃和食管糜烂等并发症。我们的初步报告研究了使用人脱细胞真皮基质(同种异体真皮)作为更合适的替代方案。本研究重点介绍了我们在使用同种异体真皮加强食管裂孔成形术修复大型食管裂孔疝方面超过1年的长期结果。

方法和材料

这是在我们大学进行的一项回顾性研究。2005年至2006年期间,52例连续的大型食管裂孔疝患者接受了同种异体真皮加强食管裂孔成形术。分析的变量包括年龄、性别、体重、身高、食管裂孔疝大小、手术时间、住院时间、随访情况和术后并发症。

结果

年龄均值为56.7岁,体重为87.9千克,身高为117厘米,疝大小为5.75厘米,手术时间为121分钟,住院时间为1.36天。并发症包括气胸3例(5.5%);肺不张1例(1.9%);尿潴留1例(1.9%);复发2例(3.8%)。

结论

使用人脱细胞真皮基质加强的腹腔镜食管裂孔疝修补术可以安全进行,住院时间短,并发症发生率低,尤其是复发率低。

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