艾滋病患者隐孢子虫感染接受螺旋霉素治疗时的肠道损伤。
Intestinal injury associated with spiramycin therapy of Cryptosporidium infection in AIDS.
作者信息
Weikel C, Lazenby A, Belitsos P, McDewitt M, Fleming H E, Barbacci M
机构信息
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
出版信息
J Protozool. 1991 Nov-Dec;38(6):147S.
PMID:1818145
Abstract
Two of three patients treated with high doses of spiramycin for Cryptosporidium infection developed acute intestinal injury. Spiramycin at high doses may be directly toxic to the intestinal epithelium and thus may have limited utility as therapy for cryptosporidiosis in AIDS patients.
摘要
三名接受大剂量螺旋霉素治疗隐孢子虫感染的患者中有两名出现了急性肠道损伤。大剂量螺旋霉素可能对肠道上皮具有直接毒性，因此作为艾滋病患者隐孢子虫病的治疗药物，其效用可能有限。
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