Pedersen Susanne S, Theuns Dominic A M J, Erdman Ruud A M, Jordaens Luc
CoRPS-Center of Research on Psychology in Somatic diseases, Tilburg University, Tilburg, The Netherlands.
Pacing Clin Electrophysiol. 2008 Jan;31(1):20-7. doi: 10.1111/j.1540-8159.2007.00921.x.
This study examined the impact of clustering of device-related concerns and Type D personality on anxiety and depressive symptoms during a six-month period and the clinical relevance of shocks, implantable cardioverter defibrillator (ICD) concerns, and Type D.
Consecutively implanted ICD patients (n = 176) completed questionnaires at baseline and six months and were divided into four risk groups: (1) No risk factors (neither ICD concerns nor Type D); (2) ICD concerns only; (3) Type D only; (4) Clustering (both ICD concerns and Type D).
The prevalence of Type D and concerns were 21.6% and 34.7%. Analysis of variance for repeated measures showed a reduction in anxiety over time (P < 0.001), with the risk groups exerting a stable (P = 0.14) but differential effect (P < 0.001); the highest level was seen in the clustering group. Similar results were found for depression, although depressive symptoms did not decrease (P = 0.08) and the impact of clustering was less clear. These results were confirmed in adjusted analysis, with shocks (P = 0.024) also being associated with anxiety but not depression. The impact of ICD concerns and Type D personality on anxiety and depression at baseline and six months was large (>or=0.8) compared to negligible to moderate for shocks (0.0-0.6).
ICD patients with psychosocial risk factor clustering had the highest level of anxiety, whereas the pattern for depression was less consistent. Shocks influenced outcomes, but the impact was smaller compared to ICD concerns and Type D personality. It may be timely to expand the focus beyond shocks when seeking to identify ICD patients at risk for adverse clinical outcome due to their psychological profile.
本研究调查了在六个月期间与设备相关的担忧和D型人格聚集对焦虑和抑郁症状的影响,以及电击、植入式心脏复律除颤器(ICD)相关担忧和D型人格的临床相关性。
连续纳入植入ICD的患者(n = 176),在基线和六个月时完成问卷调查,并分为四个风险组:(1)无风险因素(既无ICD相关担忧也无D型人格);(2)仅ICD相关担忧;(3)仅D型人格;(4)聚集组(既有ICD相关担忧又有D型人格)。
D型人格和相关担忧的患病率分别为21.6%和34.7%。重复测量方差分析显示,随着时间推移焦虑有所减轻(P < 0.001),风险组有稳定作用(P = 0.14)但有差异效应(P < 0.001);聚集组焦虑水平最高。抑郁方面也有类似结果,尽管抑郁症状没有减轻(P = 0.08),且聚集的影响不太明确。这些结果在调整分析中得到证实,电击(P = 0.024)也与焦虑相关,但与抑郁无关。与电击的可忽略到中等影响(0.0 - 0.6)相比,ICD相关担忧和D型人格在基线和六个月时对焦虑和抑郁的影响较大(≥0.8)。
具有心理社会风险因素聚集的ICD患者焦虑水平最高,而抑郁模式不太一致。电击影响结果,但与ICD相关担忧和D型人格相比影响较小。在试图识别因心理特征而有不良临床结局风险的ICD患者时,将关注重点从电击扩展到其他方面可能很及时。