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新生儿科医生的困境:极低出生体重儿的追赶生长还是有益的营养不良——最佳生长速率是多少?

The neonatologist's dilemma: catch-up growth or beneficial undernutrition in very low birth weight infants-what are optimal growth rates?

作者信息

Thureen Patti J

机构信息

University of Colorado Health Sciences Center and the Children's Hospital of Denver, Denver, CO, USA.

出版信息

J Pediatr Gastroenterol Nutr. 2007 Dec;45 Suppl 3:S152-4. doi: 10.1097/01.mpg.0000302962.08794.62.

DOI:10.1097/01.mpg.0000302962.08794.62
PMID:18185082
Abstract

As the threshold of viability decreases, clinicians who care for preterm neonates increasingly are faced with making decisions regarding feeding in a population for which there are no clear guidelines and minimal scientific data to inform optimal nutritional strategies. It is becoming more apparent that the amount of nutrition, as well as the timing of nutrient delivery, may affect long-term growth and metabolic outcomes. Both overnutrition and undernutrition at critical growth periods may have adverse effects. The risks and benefits of nutrient delivery designed to achieve "catch-up" growth need to be further identified. This article reviews both established concepts and more recently identified issues that need to be considered by the neonatologist when making feeding decisions in the very preterm neonate.

摘要

随着存活阈值的降低,照顾早产儿的临床医生越来越多地面临在一个没有明确指南且几乎没有科学数据来指导最佳营养策略的人群中做出喂养决策的问题。越来越明显的是,营养量以及营养输送的时间可能会影响长期生长和代谢结果。关键生长时期的营养过剩和营养不足都可能产生不利影响。旨在实现“追赶”生长的营养输送的风险和益处需要进一步明确。本文回顾了新生儿科医生在为极早产儿做出喂养决策时需要考虑的既定概念和最近发现的问题。

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