Kan Shigeyuki, Misaki Masaya, Koike Takahiko, Miyauchi Satoru
Kobe Advanced ICT Research Center, National Institute of Information and Communications Technology, 588-2 Iwaoka, Iwaoka-cho, Nishi-ku, Kobe-shi, Hyogo, Japan.
Neuroreport. 2008 Jan 22;19(2):133-7. doi: 10.1097/WNR.0b013e3282f3151c.
Studies on saccadic eye movements in humans and animals reported decreased cortical activation accompanying saccades in visual motion sensitive area MT+/V5, implying that the region is the neural basis of saccadic suppression. This, however, conflicts with findings that MT+/V5 is activated by saccades. As MT+/V5 can be subdivided into middle temporal (MT) and medial superior temporal (MST), these regions may have distinct functional roles that cause the discrepancy. To test this hypothesis, we compared the activation of MT with that of MST during exploratory saccades and visually guided saccades. MST was activated only during visually guided saccades, whereas MT was not activated by either. These findings support our hypothesis and suggest that the activity of these regions is differentially modulated depending on extraretinal information.
对人类和动物的眼球跳动进行的研究报告称，在视觉运动敏感区域MT+/V5中，眼球跳动会伴随皮质激活减少，这意味着该区域是眼球跳动抑制的神经基础。然而，这与MT+/V5被眼球跳动激活的研究结果相矛盾。由于MT+/V5可细分为颞中回（MT）和颞上内侧回（MST），这些区域可能具有不同的功能作用，从而导致了这种差异。为了验证这一假设，我们比较了探索性眼球跳动和视觉引导性眼球跳动期间MT和MST的激活情况。MST仅在视觉引导性眼球跳动期间被激活，而MT在两种情况下均未被激活。这些发现支持了我们的假设，并表明这些区域的活动根据视网膜外信息受到不同的调节。
