Horváth Patrícia, Kneffel Z S, Lénárd Zsuzsanna, Kispéter Z S, Petrekanits M, Pavlik G
Department of Health Sciences and Sports Medicine, Faculty of Physical Education and Sports Sciences, Semmelweis University, Budapest, Hungary.
Echocardiography. 2008 Jan;25(1):1-7. doi: 10.1111/j.1540-8175.2007.00551.x.
According to several reports, some cardiovascular signs of hypertension (left ventricular [LV] hypertrophy, impaired diastolic filling) can be found in the normotensive offspring of hypertensive parents. It is also well known that regular physical exercise decreases the risk of hypertension.
The aim of the present study is to determine whether or not regular physical training influences these early hypertensive traits in the offspring of hypertensive parents.
Echocardiographic data of 215 (144 males, 71 females) 22- to 35-year-old nonathlete and athlete offspring of hypertensive (positive family history, FH+) and normotensive parents (negative family history, FH-) were compared in a cross-sectional design.
In the nonathlete FH+ males and females, LV dimensions were not larger than in the FH- subjects. The E/A quotient was lower in the FH+ subjects in both genders. Absolute and heart rate adjusted isovolumetric relaxation times were slightly longer in the FH+ men than in their FH- peers. No differences were seen between athlete FH- and FH+ subjects.
Regular physical exercise decreases the incidence of the adverse cardiac signs, which can be associated with hypertension in the normotensive offspring of hypertensive parents.
根据多项报告，在高血压患者的血压正常的后代中可发现一些高血压的心血管体征（左心室肥厚、舒张期充盈受损）。众所周知，定期体育锻炼可降低患高血压的风险。
本研究的目的是确定定期体育锻炼是否会影响高血压患者后代的这些早期高血压特征。
采用横断面设计，比较了215名（144名男性，71名女性）22至35岁的非运动员和运动员后代的超声心动图数据，这些后代的父母分别为高血压患者（家族史阳性，FH+）和血压正常者（家族史阴性，FH-）。
在非运动员FH+男性和女性中，左心室尺寸并不比FH-受试者大。两性中FH+受试者的E/A比值均较低。FH+男性的绝对等容舒张时间和心率校正等容舒张时间比其FH-同龄人略长。运动员FH-和FH+受试者之间未观察到差异。
定期体育锻炼可降低不良心脏体征的发生率，这些体征可能与高血压患者血压正常的后代的高血压有关。
