Kiewe Philipp, Dallenbach Friederike E, Fischer Lars, Hoecht Stefan, Kombos Theodoros, Thiel Eckhard, Korfel Agnieszka
Department of Hematology, Oncology and Transfusion Medicine, Charité Campus Benjamin Franklin, Berlin, Germany.
Clin Lymphoma Myeloma. 2007 Nov;7(9):594-6. doi: 10.3816/clm.2007.n.047.
Lymphoma manifestations of the dura mater are extremely rare and have mostly been attributed to extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) type. We report a patient with an isolated meningeal tumor, identified as a B-cell lymphoproliferative disorder with typical B-cell chronic lymphocytic leukemia immunophenotype. Because of the subclinical detection of trisomy 3 in the bone marrow by cytogenetic analysis and interphase fluorescence in situ hybridization, CD5(+) MALT is an important differential diagnosis; however, to our knowledge, this entity has never been reported in the context of dural lymphoma.
硬脑膜淋巴瘤表现极为罕见，大多归因于黏膜相关淋巴组织（MALT）型结外边缘区淋巴瘤。我们报告一例孤立性脑膜肿瘤患者，经鉴定为具有典型B细胞慢性淋巴细胞白血病免疫表型的B细胞淋巴增殖性疾病。由于通过细胞遗传学分析和间期荧光原位杂交在骨髓中亚临床检测到三体3，CD5(+) MALT是一个重要的鉴别诊断；然而，据我们所知，这种实体在硬脑膜淋巴瘤的背景下从未被报道过。
