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英国的可卡因/快克可卡因消费、治疗需求、缉获量、相关犯罪、价格、平均纯度水平及死亡情况(1990 - 2004年)

Cocaine/crack cocaine consumption, treatment demand, seizures, related offences, prices, average purity levels and deaths in the UK (1990 - 2004).

作者信息

Schifano Fabrizio, Corkery John

机构信息

Pharmacy and Postgraduate Medical Schools, School of Pharmacy, University of Hertfordshire, UK.

出版信息

J Psychopharmacol. 2008 Jan;22(1):71-9. doi: 10.1177/0269881107079170.

Abstract

A recent trend of escalating use of cocaine/crack cocaine was observed in the UK. The number of mentions on death certificates; last year use of cocaine; treatment demand, number of drug offenders, seizures, prices and average purity levels were the indicators used for this descriptive and correlational study. Figures (1990-2004) were taken from official UK sources. A total of 1022 cocaine/crack cocaine death mentions (i.e. deaths from any cause where the presence of cocaine/crack cocaine was also detected) were identified, with cocaine/crack cocaine being the sole drug mentioned in 36% of cases. The number of cocaine/crack cocaine death mentions showed a year-on-year increase and correlated positively with the following cocaine (powder) figures: last year use (p < 0.001); number of offenders (p < 0.001) and number of seizures (p < 0.001), but correlated negatively with price (p < 0.001). Furthermore, the number of cocaine/crack cocaine death mentions correlated positively with the number of crack offenders (p < 0.001) and seizures (p < 0.001), but correlated negatively with both crack purity ( p < 0.001) and price (p < 0.05). With conditions of increasing drug availability having been met in the UK, decrease in cocaine prices were associated with higher consumption levels and this, in turn, contributed to the increase in number of cocaine-related fatalities. There are limitations with the information collected, since no distinction is usually made on medical death certificates between cocaine and crack cocaine. The present study being an ecological one, it proved difficult to address the role of confounding variables that may well explain some of the associations observed.

摘要

英国出现了可卡因/快克可卡因使用量不断攀升的近期趋势。死亡证明上提及的次数、去年可卡因的使用情况、治疗需求、毒品犯罪者人数、缉获量、价格及平均纯度水平是用于此项描述性和相关性研究的指标。数据(1990 - 2004年)取自英国官方来源。总共确定了1022次提及可卡因/快克可卡因导致的死亡(即因任何原因死亡且同时检测出可卡因/快克可卡因),其中36%的案例中可卡因/快克可卡因是唯一提及的毒品。可卡因/快克可卡因死亡提及次数呈逐年上升趋势,并且与以下可卡因(粉末状)数据呈正相关:去年的使用量(p < 0.001);犯罪者人数(p < 0.001)和缉获量(p < 0.001),但与价格呈负相关(p < 0.001)。此外,可卡因/快克可卡因死亡提及次数与快克可卡因犯罪者人数(p < 0.001)和缉获量(p < 0.001)呈正相关,但与快克可卡因纯度(p < 0.001)和价格(p < 0.05)均呈负相关。在英国满足了毒品可得性增加的条件下,可卡因价格下降与更高的消费水平相关,而这反过来又导致了可卡因相关死亡人数的增加。所收集的信息存在局限性,因为在医疗死亡证明上通常不会区分可卡因和快克可卡因。本研究属于生态学研究,难以解决那些很可能解释部分观察到的关联的混杂变量的作用问题。

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