INPAD National Institute on Alcohol and Drug Policies, Department of Psychiatry, São Paulo Federal University, São Paulo, Brazil.
J Subst Abuse Treat. 2011 Oct;41(3):273-8. doi: 10.1016/j.jsat.2011.03.008. Epub 2011 May 6.
Mortality is a significant outcome among Brazilian crack/cocaine-dependent patients yet not well understood and is under investigated. This study examined a range of mortality indicators within a cohort of 131 crack/cocaine-dependent patients admitted into treatment and meeting criteria for dependence of crack (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition). After 12 years of treatment discharge, 107 individuals were reassessed and 27 death cases were confirmed by official records, wherein in its majority were caused by homicide (n = 16). In this group, survival rate was 0.77 (95% confidence interval [CI] = 0.74-0.81) and previous history of IV cocaine use was identified as a predictor of mortality (2.5, 95% CI = 1.08-5.79). High mortality rates among Brazilian crack/cocaine-dependent patients, exposure to violence, and HIV/AIDS were topics discussed in this study. This research highlights the importance of ongoing programs to manage crack/cocaine use along with other treatment features within this population.
在巴西，因吸食快克可卡因而死亡是一个严重的问题，但目前仍缺乏相关研究。本研究对 131 名符合快克依赖诊断标准（《精神障碍诊断与统计手册（第四版）》）的患者进行了研究，分析了一系列死亡率指标。在治疗结束 12 年后，对 107 名患者进行了重新评估，通过官方记录确认了 27 例死亡病例，其中大多数是由于凶杀（n = 16）。在这个群体中，生存率为 0.77（95%置信区间[CI] = 0.74-0.81），静脉注射可卡因的既往史被确定为死亡率的预测因素（2.5，95%CI = 1.08-5.79）。本研究讨论了巴西快克/可卡因依赖患者的高死亡率、暴力暴露和 HIV/AIDS 等问题。这项研究强调了针对该人群持续开展管理快克/可卡因使用和其他治疗特征项目的重要性。
