Proksch E
Department of Dermatology, University of Kiel, Kiel, Germany.
Skin Pharmacol Physiol. 2008;21(2):75-80. doi: 10.1159/000112957. Epub 2008 Jan 11.
Dry skin is a common skin condition as well as a key aspect of a number of diseases such as atopic dermatitis and psoriasis but also of other diseases and systemic conditions. Dry skin has an impact on the patient in terms of discomfort, pruritus and impaired quality of life. Within the overall treatment regimen for these diseases, the use of emollients to manage dry skin plays a considerable role in managing skin conditions. In atopic dermatitis and psoriasis, emollients help to improve skin condition and to reduce pruritus alongside more potent pharmacological agents. It is important to choose an emollient that not only soothes and rehydrates the skin but also offers numerous other dermatological supporting roles, especially induction of proper epidermal differentiation. This review will explain the role of emollients within the management of diseases with dry skin as a major symptom and the components of an ideal emollient.
皮肤干燥是一种常见的皮肤状况,也是许多疾病(如特应性皮炎和银屑病)以及其他疾病和全身性疾病的一个关键方面。皮肤干燥会给患者带来不适、瘙痒和生活质量受损等影响。在这些疾病的整体治疗方案中,使用润肤剂来管理皮肤干燥在控制皮肤状况方面起着相当重要的作用。在特应性皮炎和银屑病中,润肤剂有助于改善皮肤状况,并与更强效的药物一起减轻瘙痒。选择一种不仅能舒缓和补充皮肤水分,还能发挥许多其他皮肤支持作用,特别是诱导正常表皮分化的润肤剂非常重要。本综述将解释润肤剂在以皮肤干燥为主要症状的疾病管理中的作用以及理想润肤剂的成分。