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肝血管平滑肌脂肪瘤——一种罕见的肝脏肿瘤

[Hepatic angiomyolipoma--a rare liver tumor].

作者信息

Moench C, Burck I, Bug R, Bak Y-J, Richter B, Schroeder R, Klarner A, Strey C W, Vogl T, Bechstein W

机构信息

Klinik für Allgemein- und Gefässchirurgie, Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main.

出版信息

Z Gastroenterol. 2008 Jan;46(1):54-7. doi: 10.1055/s-2007-963773.

Abstract

A 22-year-old woman was treated for a hepatic lesion with a high suspicion of a liver adenoma at another hospital. The patient presented with unspecific abdominal pain. Further physical examination was unremarkable. A biopsy of the liver lesion revealed hepatic adenoma. Because of the increasing tumour size over a one-year period the patient was referred to our department for surgical therapy. On MRI scan, the liver mass measured 10 x 9 x 9 cm in the right liver lobe with contact to the right hilum. Because of the histological signs of adenoma a right hepatic lobectomy was performed. Postoperative follow-up was uneventful. The pathological diagnosis of hepatic angiomyolipoma was obtained. Angiomyolipoma of the liver is a rare benign mesenchymal tumour often mimicking other hepatic lesions. Histological features are thick-walled blood vessels, mature fat and smooth muscle in various proportions. The biological behaviour of the tumour is benign, although distant metastases are occasionally possible. Due to the potential for malignant transformation, tumour resection should be performed.

摘要

一名22岁女性在另一家医院因高度怀疑肝腺瘤而接受了肝脏病变治疗。患者表现为非特异性腹痛。进一步体格检查无异常。肝脏病变活检显示为肝腺瘤。由于肿瘤大小在一年期间不断增大,患者被转诊至我科接受手术治疗。磁共振成像(MRI)扫描显示,肝脏肿块位于右肝叶,大小为10×9×9厘米,与右肝门相连。鉴于腺瘤的组织学特征,实施了右肝叶切除术。术后随访情况良好。最终病理诊断为肝脏血管平滑肌脂肪瘤。肝脏血管平滑肌脂肪瘤是一种罕见的良性间叶性肿瘤,常与其他肝脏病变相似。组织学特征为厚壁血管、成熟脂肪和平滑肌,比例各异。该肿瘤的生物学行为为良性,不过偶尔也可能发生远处转移。鉴于存在恶性转化的可能性,应进行肿瘤切除。

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