Katz Kenneth A, Dick Sarah E, Osterman Mark T, Junkins-Hopkins Jacqueline M
Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Cutis. 2007 Nov;80(5):429-31.
A 21-year-old female-to-male transgender individual with a history of Crohn disease presented with enlarging perianal papules that initially were misdiagnosed as condyloma acuminatum. A biopsy specimen demonstrated granulomatous inflammation characteristic of Crohn disease. Although the patient's Crohn disease had been quiescent for years, a subsequent evaluation revealed the presence of a rectal stricture that was then dilated. Perianal skin tags with granulomatous inflammation are one of many perianal manifestations of Crohn disease. Increasing numbers or size of these lesions may herald worsening of more proximal Crohn disease, as in our patient. We review the epidemiology, classification, and management of perianal skin tags in patients with Crohn disease.
一名21岁的女变男跨性别者，有克罗恩病病史，出现肛周丘疹增大，最初被误诊为尖锐湿疣。活检标本显示出克罗恩病特有的肉芽肿性炎症。尽管患者的克罗恩病已静止多年，但随后的评估发现存在直肠狭窄，随后进行了扩张。伴有肉芽肿性炎症的肛周皮赘是克罗恩病许多肛周表现之一。正如我们的患者一样，这些病变数量增加或体积增大可能预示着更近端的克罗恩病病情恶化。我们回顾了克罗恩病患者肛周皮赘的流行病学、分类和管理。
