单纯疱疹病毒（HSV）体外诱导的细胞转化。注释III。某些HSV - 2转化细胞系的致癌性。
Cellular transformation in vitro induced by herpes simplex virus (HSV). Note III. Oncogenicity of some HSV-2-transformed cell lines.
作者信息
Sahnazarov N, Muţiu A, Gruia M, Surdan C, Cernescu C, Gologan R, Cajal N
出版信息
Virologie. 1976 Jan-Mar;27(1):47-50.
PMID:181902
Abstract
At high in vitro passage levels HSV-2-transformed hamster and rat cell lines were oncogenic for the homologous animals, inducing fusocellular or round-cell sarcomas. The cell lines obtained by in vitro cultivation of the tumors were free of infectious virus.
摘要
在高体外传代水平时，单纯疱疹病毒2型（HSV-2）转化的仓鼠和大鼠细胞系对同种动物具有致癌性，可诱导梭形细胞或圆形细胞肉瘤。通过体外培养肿瘤获得的细胞系不含传染性病毒。
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