Kumaravelu Priya G, Vella Sandra, Pontes J Edson, Heath Elisabeth I
Department of Internal Medicine, Wayne State University, Detroit, MI 48201, USA.
Urol Oncol. 2008 Jan-Feb;26(1):53-5. doi: 10.1016/j.urolonc.2006.12.017. Epub 2007 Nov 7.
Metastatic undifferentiated sex cord-stromal testis tumors are uncommon. We would like to present a rare case of undifferentiated sex cord-stromal testis tumor with brain metastasis. After presenting with a painless right testicular mass, the patient underwent right radical orchiectomy and retroperitoneal lymph node dissection. One month later, the patient had no visible evidence of tumor recurrence on the follow-up computed tomography of the chest, abdomen, and pelvis. Three months after the first follow-up, the patient was readmitted for new onset of shortness of breath, and 7th and 12th cranial nerve palsy. Computed tomography of the chest and magnetic resonance imaging of the brain showed evidence of distant metastasis. To our knowledge, undifferentiated sex cord-stromal tumor with brain metastasis has not been reported. As with any new onset neurologic deficits in patients with solid tumors, the presence of brain metastases should be considered.
转移性未分化性索间质睾丸肿瘤并不常见。我们在此呈现一例罕见的伴有脑转移的未分化性索间质睾丸肿瘤病例。患者出现无痛性右侧睾丸肿块后,接受了右侧根治性睾丸切除术及腹膜后淋巴结清扫术。一个月后,在胸部、腹部和骨盆的随访计算机断层扫描中未发现肿瘤复发的明显迹象。首次随访三个月后,患者因新发气短及第7和第12颅神经麻痹再次入院。胸部计算机断层扫描和脑部磁共振成像显示有远处转移的证据。据我们所知,伴有脑转移的未分化性索间质肿瘤尚未见报道。对于实体瘤患者出现的任何新发神经功能缺损,都应考虑存在脑转移的可能。