Study of the intramolecular cyclization of N-methyl-3-phenyl-N-(2-(E)-phenylethenyl)-trans(cis)-oxiranecarboxamide--syntheses of Homoclausenamide and Dehydroclausenamide.
作者信息
Ma Nianchun, Wu Kemei, Huang Liang
机构信息
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
出版信息
Eur J Med Chem. 2008 Aug;43(8):1781-4. doi: 10.1016/j.ejmech.2007.11.022. Epub 2007 Dec 7.
PMID:18191305
Abstract
Homoclausenamide was synthesized for the first time, and the intramolecular cyclization study of N-methyl-3-phenyl-N-(2-(E)-phenylethenyl)-trans(cis)-oxiranecarboxamide well demonstrated how the stereochemistry affects the cyclization paths.
摘要
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