兔睾丸颗粒细胞瘤：细胞学、组织学、免疫组织化学及电子显微镜特征

Granular cell tumor in the testis of a rabbit: cytologic, histologic, immunohistochemical, and electron microscopic characterization.

作者信息

Irizarry-Rovira A R, Lennox A M, Ramos-Vara J A

机构信息

Toxicology and Drug Disposition, Lilly Research Laboratories, a Division of Eli Lilly and Company, Greenfield, IN 46140, USA.

出版信息

Vet Pathol. 2008 Jan;45(1):73-7. doi: 10.1354/vp.45-1-73.

DOI:10.1354/vp.45-1-73

PMID:18192581

Abstract

An adult pet rabbit (Oryctolagus cuniculus) presented with a progressively enlarging left testicle. Because neoplasia was suspected, the testicle was removed. Pathologic evaluation (exfoliative cytology, histopathology, immunohistochemistry, electron microscopy) indicated that the tumor was an intratesticular granular cell tumor. Granular cell tumor has not been described in rabbits before and has not been described in the testes of animals or postnatal humans. Granular cell tumor should be included as a differential diagnosis of testicular tumors, particularly Leydig cell tumor, because of potential histologic similarities.

摘要

一只成年宠物兔（穴兔）左侧睾丸逐渐肿大。由于怀疑是肿瘤，遂将睾丸切除。病理评估（脱落细胞学、组织病理学、免疫组织化学、电子显微镜检查）显示该肿瘤为睾丸内颗粒细胞瘤。颗粒细胞瘤此前在兔中未见报道，在动物睾丸或出生后的人类中也未被描述过。由于存在潜在的组织学相似性，颗粒细胞瘤应作为睾丸肿瘤，尤其是莱迪希细胞瘤的鉴别诊断之一。