Joesoef M Riduan, Weinstock Hillard S, Johnson Robert E
Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
Sex Transm Dis. 2008 Apr;35(4):368-71. doi: 10.1097/OLQ.0b013e31815ea2bb.
To evaluate factors associated with recurrent chlamydial infection and failure to return for retesting in socioeconomically disadvantaged women (aged 16-24 years) entering the National Job Training Program, 1998--2005.
To evaluate sociodemographic characteristics of young women associated with recurrent chlamydial infection.
We computed chlamydia prevalence at initial visit and recurrent infection (defined as a positive chlamydia test 1-2 months after completing treatment) and percent of infected women who were retested by sociodemographic variables.
At entrance, women had a high prevalence of chlamydia infection (10.7%). Chlamydia prevalence varied by age, race/ethnicity, and place of residence (South, Midwest, Northeast, and West), year of test, and type of test. Among women infected at initial visit, younger aged women (16-17 years), blacks and Hispanics, those who resided in the South and Midwest, and those tested in 1998--2000 were less likely to be retested. Of the 13,550 infected women, 5,892 (43.5%) were retested. Of those retested, 332 (5.6%) had recurrent infection 1-2 months after completing treatment. Although chlamydia prevalence at retesting did not differ significantly by sociodemographic characteristics, the pattern of the prevalence was similar to the pattern at the initial test. Multivariate logistic regression analyses showed similar findings.
The high prevalence of recurrent infection in these women may be due to reinfection and/or treatment failure. The findings of this analysis underscore the need for retesting infected women regardless of their demographic characteristics.
评估1998 - 2005年参加国家职业培训计划的社会经济弱势女性(年龄16 - 24岁)衣原体反复感染及未返回接受重新检测的相关因素。
评估与衣原体反复感染相关的年轻女性的社会人口学特征。
我们根据社会人口学变量计算了初次就诊时的衣原体患病率、反复感染率(定义为完成治疗后1 - 2个月衣原体检测呈阳性)以及接受重新检测感染女性的百分比。
入组时,女性衣原体感染患病率较高(10.7%)。衣原体患病率因年龄、种族/族裔、居住地区(南部、中西部、东北部和西部)、检测年份及检测类型而异。初次就诊时感染的女性中,年龄较小的女性(16 - 17岁)、黑人和西班牙裔、居住在南部和中西部的女性以及1998 - 2000年接受检测的女性接受重新检测的可能性较小。在13550名感染女性中,5892名(43.5%)接受了重新检测。在接受重新检测的女性中,332名(5.6%)在完成治疗后1 - 2个月出现反复感染。尽管重新检测时衣原体患病率在社会人口学特征方面无显著差异,但患病率模式与初次检测时相似。多因素逻辑回归分析显示了类似的结果。
这些女性反复感染率高可能是由于再次感染和/或治疗失败。该分析结果强调,无论感染女性的人口学特征如何,都有必要对其进行重新检测。