Simić D, Subota N
Srp Arh Celok Lek. 1992 Jun;120 Suppl 4:71-3.
Hypertension is the essential risk factor in the morbidity and mortality from cardiovascular complications. The basic treatment consists of drugs from four groups--diuretics, beta blockers, ACE inhibitors and calcium-channel blockers--and the choice must be individualized, especially in patients with mild hypertension. The drug and the dosage regimen depends on the individual characteristics of patient obtained from psychological, psychometric and affective examination. The conducted research shows that beta blockers are effective antihypertensive agents and that they improve the overall quality of life in sense of well being, psychological symptoms and capabilities for physical, emotional, social and intellectual functioning. Low incidence of CNS side effects in patients on atenolol may be due to its hydrophilicity.
高血压是心血管并发症发病和死亡的主要危险因素。基本治疗包括使用四类药物——利尿剂、β受体阻滞剂、血管紧张素转换酶抑制剂和钙通道阻滞剂——治疗方案必须个体化,尤其是轻度高血压患者。药物及其剂量方案取决于通过心理、心理测量和情感检查获得的患者个体特征。所进行的研究表明,β受体阻滞剂是有效的抗高血压药物,并且它们在幸福感、心理症状以及身体、情感、社交和智力功能能力方面改善了整体生活质量。服用阿替洛尔的患者中枢神经系统副作用发生率较低可能归因于其亲水性。