Rahn K H, Hohage H
Medizinische Poliklinik, Westfälischen Wilhelms-Universität Münster.
Z Kardiol. 1994;83 Suppl 6:159-62.
Antihypertensive therapy improves the long-term prognosis of patients with mild to moderate essential hypertension and is able to prevent complications. This is also true for the elderly patient with hypertension. A considerable percentage of patients with mild essential hypertension can be adequately treated without drugs. If drug treatment is required, diuretics, beta-blockers, calcium antagonists, and ACE-inhibitors are the agents of first choice. For the individual patient, the appropriate drug should be chosen on the basis of efficacy, lack of side-effects, and depending upon additional diseases, such as cardiac failure, coronary heart disease and renal failure. Only if these selection criteria are fulfilled should differences in prices of the various groups of antihypertensive agents be considered.
抗高血压治疗可改善轻至中度原发性高血压患者的长期预后，并能预防并发症。老年高血压患者亦是如此。相当一部分轻度原发性高血压患者无需药物即可得到充分治疗。如果需要药物治疗，利尿剂、β受体阻滞剂、钙拮抗剂和血管紧张素转换酶抑制剂是首选药物。对于个体患者，应根据疗效、无副作用以及取决于其他疾病，如心力衰竭、冠心病和肾衰竭等情况来选择合适的药物。只有满足这些选择标准时，才应考虑各类抗高血压药物价格上的差异。
