Kordac V, Kaláb M
Acta Hepatogastroenterol (Stuttg). 1976 Jun;23(3):186-93.
A study was performed on a group of 75 patients with primary liver carcinoma (PLC) treated at the 1st Medical Department in Prague during past 24 years. The average age of patients when they died was 59.9 years. 86.7 per cent of the patients were men; in 88.0 per cent of cases PLC was associated with liver cirrhosis. It was found that the frequency of PLC incidence is increasing. Case histories, subjective complaints and laboratory findings were analyzed in these patients. The diagnostic contribution of some examination methods was evaluated (laparoscopy with the aimed liver biopsy in 50% of the cases, isotopic methods in 34.6% of cases, roentgenologic methods in 36.0% of cases, detection of alpha-1 fetoprotein in serum in 55.5% of cases). The analysis of causes of death was also performed. Histologic classification proved the hepatocellular carcinoma in 94.6 per cent of patients, the cholangiocellular carcinoma was found only in 4 patients. The agreement of clinical diagnoses with the pathologic-anatomical diagnosis was found in 70.6% of cases.
对过去24年在布拉格第一内科接受治疗的75例原发性肝癌（PLC）患者进行了一项研究。患者死亡时的平均年龄为59.9岁。86.7%的患者为男性；88.0%的病例中PLC与肝硬化有关。发现PLC的发病率在上升。分析了这些患者的病历、主观症状和实验室检查结果。评估了一些检查方法的诊断价值（50%的病例采用腹腔镜下靶向肝活检，34.6%的病例采用同位素方法，36.0%的病例采用放射学方法，55.5%的病例检测血清甲胎蛋白）。还对死亡原因进行了分析。组织学分类显示94.6%的患者为肝细胞癌，仅4例为胆管细胞癌。70.6%的病例临床诊断与病理解剖诊断相符。
