Pichard E, Fisch A, Sebbag R, Maiga B, Fongoro S, Ag Rhaly A, Gentilini M
Ecole Nationale de Médecine et de Pharmacie, Bamako.
Bull Soc Pathol Exot. 1991;84(5 Pt 5):783-93.
A new method for iodine deficiency disorders prevention is tested during one year in a rural area of Mali. Silicone and sodium iodide made diffusers are set up inside 2 villages' drillings. Their efficiency is compared with a placebo. Supervision criteria are evolution of goiter, rates of iodine in water and ioduria of the population, specially women and children. In the treated villages a decrease of goiters' size of the younger people is observed. Iodine rates in treated drillings water stay during 12 months between 150 and 300 micrograms/l with a minimum intake of 150 micrograms/day/person. The means of ioduria rates from less than 25 micrograms/l before treatment (severe deficiency) increase to more than 100 micrograms/l after six months of treatment (no deficiency).
在马里的一个农村地区，一种预防碘缺乏症的新方法经过了为期一年的测试。由硅酮和碘化钠制成的扩散器被安装在两个村庄的水井中。将它们的效果与安慰剂进行比较。监测标准包括甲状腺肿的变化、水中碘含量以及人群（特别是妇女和儿童）的尿碘水平。在接受治疗的村庄中，观察到年轻人甲状腺肿的大小有所减小。经过处理的水井水中碘含量在12个月内保持在150至300微克/升之间，每人每天的最低摄入量为150微克。治疗前尿碘水平低于25微克/升（严重缺乏），经过六个月的治疗后，尿碘水平均值升至100微克/升以上（无缺乏）。
