Liou Li-Min, Lan Sheng-Hsing, Lai Chiou-Lian
Department of Neurology, Kaohsiung Municipal Hsiaokang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Neurologist. 2008 Jan;14(1):40-2. doi: 10.1097/NRL.0b013e3180d0a391.
Dengue fever, especially dengue hemorrhagic fever, often presents with thrombocytopenia and hemorrhagic phenomenon. Neurologic manifestations are uncommon.
We report a case of dengue fever with thrombocytopenia and ischemic stroke. Only supportive treatment was instituted. The neurologic deficits of the patient were initially progressive and then improved. The platelet count correlated well with the disease severity and the neurologic deficits. The time course was compatible with the critical stage in dengue hemorrhagic fever. Some studies show that immunomodulators or immunosuppressants may reverse thrombocytopenia such that the bleeding episodes improve rapidly.
Dengue fever may present as ischemic stroke.
登革热，尤其是登革出血热，常伴有血小板减少和出血现象。神经系统表现并不常见。
我们报告一例伴有血小板减少和缺血性中风的登革热病例。仅采取了支持性治疗。患者的神经功能缺损最初呈进行性，随后有所改善。血小板计数与疾病严重程度及神经功能缺损密切相关。病程与登革出血热的关键阶段相符。一些研究表明，免疫调节剂或免疫抑制剂可能会逆转血小板减少，从而使出血发作迅速改善。
登革热可能表现为缺血性中风。
