Martin T C, Van Longhuyzen H, Bennett B, Peterson S, Beazer C, Thomas C V
The Intensive Care Unit, Holberton Hospital, St John's, Antigua.
West Indian Med J. 2007 Sep;56(4):326-9.
This study was done to assess the age-specific incidence of admission for acute myocardial infarction in Antigua and Barbuda from 1990 to 2001. A retrospective review of Intensive Care Unit admissions for possible acute myocardial infarction was performed. Data obtained included age, gender, country of residence, electrocardiogram, creatine kinase results and intensive care unit outcome. There were, 250 admissions, 194 (78%) having data available for review. Acute myocardial infarction was found in 107/194 (55.2%) patients, age 59.9 +/- 13.7 years, 28% female, 70% from Antigua and Barbuda, 90/107 (85%) were between 35 and 75 years old. The incidence would be 7.5 per year or 9.7 per year if the confirmation rate documented was similar for all admissions. With a yearly population of 9555 men age 35 to 75 years in Antigua and Barbuda, with men accounting for 72% of acute myocardial infarctions, the incidence rate was 0.57 (confirmed) to 0.73 (all admissions) per year per 1000 men. For women, the yearly population was 10822 age 35 to 75 years, and the incidence rate was 0.19 to 0.24 per year per 1000 women. The mortality rate was 12/107 (11.2%), with women being older (67 vs 57 years, p = 0.001) and dying more often (17% vs 9%) compared with men. The mortality rate in the Intensive Care Unit was 0.07 per year for men, 0.04 per year for women per 1000 aged 35 to 75 years. In the United States of America (USA), the admission rate is 4.1 for men and 1.8 for women per year per 1000 aged 35 to 75 years; the mortality rate is 1.0 for men and 0.5 for women per year per 1000 aged 35 to 75 years. Rates of admission to the Intensive Care Unit for acute myocardial infarction in Antigua and Barbuda are 20%, and mortality rates are 10% of those reported in the USA.
本研究旨在评估1990年至2001年期间安提瓜和巴布达急性心肌梗死的年龄特异性入院发病率。对重症监护病房可能为急性心肌梗死的入院病例进行了回顾性研究。获得的数据包括年龄、性别、居住国家、心电图、肌酸激酶结果及重症监护病房结局。共有250例入院病例，其中194例（78%）有可供审查的数据。194例患者中有107例（55.2%）被诊断为急性心肌梗死，年龄为59.9±13.7岁，女性占28%，70%来自安提瓜和巴布达，107例中有90例（85%）年龄在35至75岁之间。如果所有入院病例的确诊率相似，发病率将为每年7.5例或每年9.7例。在安提瓜和巴布达，年龄在35至75岁的男性每年有9555人，男性占急性心肌梗死病例的72%，发病率为每1000名男性每年0.57例（确诊）至0.73例（所有入院病例）。对于女性，年龄在35至75岁的每年有10822人，发病率为每1000名女性每年0.19至0.24例。死亡率为107例中的12例（11.2%），女性年龄更大（67岁对57岁，p = 0.001），与男性相比死亡更频繁（17%对9%）。在重症监护病房，年龄在35至75岁的男性死亡率为每年0.07例，女性为每年0.04例。在美国，年龄在35至75岁的男性每年入院率为每1000人4.1例，女性为每1000人1.8例；年龄在35至75岁的男性每年死亡率为每1000人1.0例，女性为每1000人0.5例。安提瓜和巴布达急性心肌梗死的重症监护病房入院率为美国报告率的20%，死亡率为10%。
