Carrico Donna J, Peters Kenneth M, Diokno Ananias C
William Beaumont Hospital, Department of Urology, Royal Oak, MI 48073, USA.
J Altern Complement Med. 2008 Jan-Feb;14(1):53-60. doi: 10.1089/acm.2007.7070.
In the United States, more than 1 million women and men are affected with interstitial cystititis (IC), which is a clinical syndrome involving urinary urgency, frequency, and pelvic pain. A review of the literature revealed that there are no studies showing the effect of guided imagery in women with IC. The purpose of this clinical investigation was to explore the effect of guided imagery on pelvic pain and urinary symptoms in women with IC symptoms.
Thirty (30) women with diagnosed IC were randomized into 2 equal groups. One group (treatment) listened to a 25-minute guided imagery compact disc (CD), that was created specifically for women with pelvic pain and IC, twice a day for 8 weeks. The control group rested for 25 minutes twice daily for 8 weeks. Because no guided imagery CDs specifically for women with IC were found on the commercial market, the authors created a script and recorded the CD specifically for women with IC and pelvic pain. The focus of this guided imagery CD was on healing the bladder, relaxing the pelvic-floor muscles, and quieting the nerves specifically involved in IC. Baseline and end-of-study assessment questionnaires (Interstitial Cystitis Symptom Index & Problem Index [IC-SIPI], IC Self-Efficacy Scale, a visual analogue [VAS] scale for pain, and a global response assessment [GRA]), 2-day voiding diaries, and 24-hour pain diaries were completed by the subjects and were evaluated using SPSS (Chicago, IL).
More than 45% of the treatment group were responders to guided imagery therapy noting a moderate or marked improvement on the GRA. Pain scores and episodes of urgency significantly decreased in the treatment group. Responders had significant reductions in IC-SIPI scores (problem index, p = 0.006; symptom index, p = 0.004). In addition, responders on the GRA had significant (p = 0.039) improvements in mean pain scores from 5.50 to 2.57 at the end of the study in contrast to the nonresponders, whose pain levels remained the same (4.89 to 4.39).
This is the first study providing preliminary data supporting the use of guided imagery as a potential therapy for IC. Guided imagery may be a useful tool to offer women with IC for pain and IC symptom management. It is an intervention without negative side-effects, is readily available, and shows a trend toward improvement of IC symptoms.
在美国,超过100万女性和男性受到间质性膀胱炎(IC)的影响,这是一种涉及尿急、尿频和盆腔疼痛的临床综合征。文献综述显示,尚无研究表明引导式意象对患有IC的女性有何影响。本临床研究的目的是探讨引导式意象对有IC症状女性的盆腔疼痛和泌尿系统症状的影响。
30名被诊断为IC的女性被随机分为两组。一组(治疗组)每天听两次专门为患有盆腔疼痛和IC的女性制作的25分钟引导式意象光盘(CD),持续8周。对照组每天休息两次,每次25分钟,持续8周。由于在商业市场上未找到专门针对患有IC的女性的引导式意象CD,作者编写了一个脚本并专门为患有IC和盆腔疼痛的女性录制了CD。该引导式意象CD的重点是治愈膀胱、放松盆底肌肉以及使与IC具体相关的神经平静下来。受试者完成了基线和研究结束时的评估问卷(间质性膀胱炎症状指数和问题指数[IC-SIPI]、IC自我效能量表、疼痛视觉模拟[VAS]量表以及总体反应评估[GRA])、2天排尿日记和24小时疼痛日记,并使用SPSS(伊利诺伊州芝加哥)进行评估。
超过45%的治疗组对引导式意象疗法有反应,在总体反应评估中显示出中度或显著改善。治疗组的疼痛评分和尿急发作次数显著减少。有反应者的IC-SIPI评分显著降低(问题指数,p = 0.006;症状指数,p = 0.004)。此外相比无反应者,在总体反应评估中有反应者在研究结束时平均疼痛评分从5.50显著改善至2.57(p = 0.039),无反应者的疼痛水平保持不变(从4.89至4.39)。
这是第一项提供初步数据支持将引导式意象作为IC潜在治疗方法的研究。引导式意象可能是为患有IC女性进行疼痛和IC症状管理的有用工具。它是一种无负面副作用、易于获得且显示出IC症状改善趋势的干预措施。