Bueno T M, Diz A I, Cervera P Q, Pérez-Rodríguez J, Quero J
Neonatal Unit, La Paz Children's Hospital, Madrid, Spain.
J Perinatol. 2008 Apr;28(4):282-6. doi: 10.1038/sj.jp.7211923. Epub 2008 Jan 17.
To report the experience of peripheral insertion of double-lumen central catheters (PIDLCC) in preterm and term newborn infants and to analyze the technical characteristics of the procedure and any observed complications.
Retrospective review of 61 newborns that had a PIDLCC between 2003 and 2006. The study comprised clinical data analysis, anthropometrics, indications, duration, complications and reasons for withdrawal of the catheters.
Weight of the patients was <1 kg in 10%, and >2 kg in 75%. Catheters tip placement was as aimed, mostly superior cava vein (SCV), in 65.5%, and subclavian vein in remaining 34.5% and average duration of catheterization was 13.5+/-9.6 and 8.9+/-5.8 days, respectively. Blood sampling through both lumens was possible especially when the tip was at SCV. Reasons for catheter withdrawal were end of indication (45.9%), phlebitis/edema (21.3%), suspected infection (3.2%), accidental withdrawal (3.2%) and rupture of proximal end (3.2%). In three (4.9%) patients, withdrawal was due to serious complications (two cases of pleural leakage of infusion fluid and one breakage of the metallic guide). About 16.3% of the patients died with the catheter still in situ. Infection findings were positive tip culture (14.7%) and catheter-related sepsis (3.2%).
Insertion of PIDLCC is possible in neonates. The incidence of complications, mostly mechanical, requires careful evaluation of indications, and strict adherence to the procedure of insertion and manipulation.
报告双腔中心静脉导管外周置入术(PIDLCC)在早产儿和足月儿中的应用经验,并分析该操作的技术特点及观察到的任何并发症。
回顾性分析2003年至2006年间接受PIDLCC的61例新生儿。该研究包括临床数据分析、人体测量学、适应证、置管时间、并发症及导管拔除原因。
10%的患者体重<1kg,75%的患者体重>2kg。导管尖端位置达到预期,大部分位于上腔静脉(SCV),占65.5%,其余34.5%位于锁骨下静脉,平均置管时间分别为13.5±9.6天和8.9±5.8天。通过两个腔进行血液采样是可行的,尤其是当尖端位于SCV时。导管拔除的原因包括适应证结束(45.9%)、静脉炎/水肿(21.3%)、疑似感染(3.2%)、意外拔除(3.2%)和近端破裂(3.2%)。3例(4.9%)患者因严重并发症(2例输液液体胸膜渗漏和1例金属导丝断裂)而拔除导管。约16.3%的患者在导管仍在位时死亡。感染相关结果包括尖端培养阳性(14.7%)和导管相关败血症(3.2%)。
新生儿可行PIDLCC置入术。并发症发生率,主要是机械性并发症,需要仔细评估适应证,并严格遵守置入和操作程序。