Pires Marcelle Cristina da Silva, Frota Karla de Sousa, Martins Junior Paulo de Oliveira, Correia Amabel Fernandes, Cortez-Escalante Juan José, Silveira Celeste Aída
Universidade de Brasília, Brasília, DF.
Rev Soc Bras Med Trop. 2007 Nov-Dec;40(6):643-7. doi: 10.1590/s0037-86822007000600009.
Urinary tract infection is among the most common infectious diseases in clinical medicine, and knowledge of its epidemiology and the sensitivity profile of the etiological agents is mandatory. The aim of this study was to identify the most frequent etiological agents and the profile of sensitivity to antimicrobial agents of the bacteria isolated from urine cultures from outpatients at the University Hospital of Brasília between 2001 and 2005. From analyses at the hospitals microbiology laboratory, there were 2,433 positive urine cultures. Escherichia coli was the most commonly isolated bacteria (62.4%), followed by Klebsiella pneumoniae (6.8%) and Proteus mirabilis (4.7%). Escherichia coli showed the highest sensitivity to amikacin (98.6%), gentamicin (96.2%), nitrofurantoin (96.3%) and the quinolones ciprofloxacin (90.9%) and norfloxacin (89.8%), with low sensitivity to sulfamethoxazole-trimethoprim (50.6%). The others bacteria presented similar sensitivity profiles. In conclusion, Escherichia coli was the most commonly isolated bacteria, and it was highly sensitive to aminoglycosides, nitrofurantoin and quinolones.
尿路感染是临床医学中最常见的传染病之一，了解其流行病学以及病原体的敏感性概况是必不可少的。本研究的目的是确定2001年至2005年间从巴西利亚大学医院门诊患者尿液培养物中分离出的细菌中最常见的病原体以及对抗菌药物的敏感性概况。通过医院微生物实验室的分析，有2433份尿液培养呈阳性。大肠埃希菌是最常分离出的细菌（62.4%），其次是肺炎克雷伯菌（6.8%）和奇异变形杆菌（4.7%）。大肠埃希菌对阿米卡星（98.6%）、庆大霉素（96.2%）、呋喃妥因（96.3%）以及喹诺酮类药物环丙沙星（90.9%）和诺氟沙星（89.8%）显示出最高的敏感性，对磺胺甲恶唑-甲氧苄啶敏感性较低（50.6%）。其他细菌呈现出相似的敏感性概况。总之，大肠埃希菌是最常分离出的细菌，并且它对氨基糖苷类、呋喃妥因和喹诺酮类药物高度敏感。
