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子宫内膜癌术前放射治疗:一项临床试验的初步报告。

Preoperative radiation therapy in endometrial carcinoma: preliminary report of a clinical trial.

作者信息

Weigensberg I J

出版信息

AJR Am J Roentgenol. 1976 Aug;127(2):319-23. doi: 10.2214/ajr.127.2.319.

DOI:10.2214/ajr.127.2.319
PMID:182014
Abstract

A total of 91 patients with stage I endometrial adenocarcinoma who were referred for radiation prior to hysterectomy were randomly allocated to recieve either intracavitary or external bean irradiation. Total abdominal hysterectomy was done 4-8 weeks later. The 53 patients who received intracavitary irradiation had an actuarial 5 year disease-free survival rate of 75%; the survival rate of the 38 patients in the external beam group was 48%. Nine patients in the external beam group had recurrence or metastases compared to two in the intracavitary group. These recurrences were predominantly pelvic. Complications were also more frequent in the external beam group. These results demonstrate that intracavitary radiation is superior to external beam radiation using the regiments described.

摘要

共有91例I期子宫内膜腺癌患者在子宫切除术前被转诊接受放疗,他们被随机分配接受腔内照射或体外照射。4至8周后进行全腹子宫切除术。接受腔内照射的53例患者的5年无病生存率为75%;体外照射组38例患者的生存率为48%。体外照射组有9例患者复发或转移,而腔内照射组为2例。这些复发主要发生在盆腔。体外照射组的并发症也更常见。这些结果表明,使用所述方案时,腔内放疗优于体外放疗。

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