Gruppioni G, Brasili Gualandi P, Vona G
Department of Environmental Science, University of L'Aquila.
Gene Geogr. 1991 Apr-Aug;5(1-2):95-102.
This study examines the distribution of properdin factor B by means of electrophoresis on cellulose acetate in a sample of 780 individuals from seven historical/geographical areas of Sardinia: Nurra, Goceano, Nuorese, Arborea, Sarcidano, Ogliastra, Campidano di Cagliari. The gene frequencies obtained for the total sample are BFS = 0.595, BFF = 0.227, BFS1 = 0.012, BFF1 = 0.166. Division of the total sample into subsamples has highlighted some noticeable differences both among the historical/geographical areas considered and with mainland Italy. In Sardinia relatively low frequencies of the allele BFS are accompanied by exceptionally high incidences of the variant allele BFF1, which reaches a maximum in the Goceano area (0.2143).
本研究通过醋酸纤维素电泳法，对来自撒丁岛七个历史/地理区域（努拉、戈谢亚诺、努奥雷斯、阿尔博雷亚、萨尔西达诺、奥利亚斯特拉、卡利亚里坎皮达诺）的780名个体样本中的备解素因子B分布情况进行了研究。总样本获得的基因频率为BFS = 0.595，BFF = 0.227，BFS1 = 0.012，BFF1 = 0.166。将总样本划分为子样本后发现，在所考虑的历史/地理区域之间以及与意大利大陆相比，存在一些显著差异。在撒丁岛，等位基因BFS的频率相对较低，同时变异等位基因BFF1的发生率异常高，在戈谢亚诺地区达到最高值（0.2143）。
