Al-Ghwery Said, Al-Asmari Abdulrahman
Department of Pediatrics, Riyadh Military Hospital, Riyadh, Saudi Arabia.
Saudi J Kidney Dis Transpl. 2004 Jan-Mar;15(1):75-8.
In a retrospective survey, 75 children with chronic renal failure (CRF) referred to our renal unit during 1989-2002 were studied. Their ages ranged from 10 days to 14 years (male to female ratio 1.7:1) and 64% of the cases were under one year of age. The mean annual incidence of CRF was 7.14%. All the patients had irreversible levels for creatinine corresponding approximately to a glomerular filtration rate less than 50 ml/min/1.73 m 2 . The main etiological groups of primary renal disease were malformation of the urinary tract (45.3%), renal hypoplasia/dysplasia (18.7%), hereditary disorders (9.3%), glomerulopathies (6.7%), nephrotic syndrome (5.3%), while urinary system anomalies only made up 2.5% of the cases. The remaining (12%) had CRF of unknown etiology. Twenty-eight patients were treated for CRF of whom 13 patients were started on ambulatory peritoneal dialysis and five, on hemodialysis. Seven patients have undergone transplantation and three died.
在一项回顾性调查中,对1989年至2002年间转诊至我们肾脏科的75例慢性肾衰竭(CRF)患儿进行了研究。他们的年龄从10天至14岁不等(男女比例为1.7:1),64%的病例年龄在1岁以下。CRF的年平均发病率为7.14%。所有患者的肌酐水平均不可逆,大致相当于肾小球滤过率低于50 ml/min/1.73 m²。原发性肾脏疾病的主要病因组为泌尿系统畸形(45.3%)、肾发育不全/发育异常(18.7%)、遗传性疾病(9.3%)、肾小球病(6.7%)、肾病综合征(5.3%),而泌尿系统异常仅占病例的2.5%。其余(12%)患者的CRF病因不明。28例患者接受了CRF治疗,其中13例开始进行非卧床腹膜透析,5例开始进行血液透析。7例患者接受了移植手术,3例死亡。