负载于氟代硅胶上的无膦全氟标记钯纳米粒子：在Heck反应中的应用。

Phosphine-free perfluoro-tagged palladium nanoparticles supported on fluorous silica gel: application to the Heck reaction.

作者信息

Bernini Roberta, Cacchi Sandro, Fabrizi Giancarlo, Forte Giovanni, Niembro Sandra, Petrucci Francesco, Pleixats Roser, Prastaro Alessandro, Sebastián Rosa Maria, Soler Roger, Tristany Mar, Vallribera Adelina

机构信息

Dipartimento A.B.A.C., Università della Tuscia e Consorzio Universitario La Chimica per l'Ambiente, Via S. Camillo De Lellis, 01100 Viterbo, Italy.

出版信息

Org Lett. 2008 Feb 21;10(4):561-4. doi: 10.1021/ol7024845. Epub 2008 Jan 19.

DOI:10.1021/ol7024845

PMID:18205367

Abstract

The immobilization of phosphine-free perfluoro-tagged palladium nanoparticles Pd-1 on fluorous silica gel (FSG) and their utilization in the Heck reaction have been investigated. High yields of vinylic substitution products have been obtained. Recycling studies have shown that the solid-supported palladium catalyst can be readily recovered and reused several times without significant loss of activity. Reactions and recovery of the solid-supported palladium catalyst system can be carried out in the presence of air, without any particular precaution.

摘要

研究了无膦全氟标记钯纳米颗粒Pd-1在氟硅胶（FSG）上的固定化及其在Heck反应中的应用。已获得高产率的乙烯基取代产物。回收研究表明，固体负载钯催化剂可以很容易地回收并重复使用几次，而活性没有明显损失。固体负载钯催化剂体系的反应和回收可以在空气中进行，无需任何特殊防护措施。