Ricard A S, Gindre A, Laurentjoye M, Fernandez P, Guyot M, Demeaux H, Siberchicot F, Majoufre-Lefebvre C
Service de chirurgie maxillofaciale, CHU Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
Rev Stomatol Chir Maxillofac. 2008 Apr;109(2):86-90. doi: 10.1016/j.stomax.2007.11.002. Epub 2008 Jan 18.
The aim of our retrospective study was to evaluate the role of PET-CT in the management of upper-aerodigestive tract (UADT) squamous-cell carcinomas.
Our study included 43 patients with UADT squamous-cell carcinomas having undergone PET-CT for: initial staging (n=20), diagnosis of recurrent disease (n=16), and response to treatment (n=7).
PET-CT diagnosed distant metastases missed by conventional imaging in four patients (20%) in initial staging, four patients (25%) in diagnosis of recurrent disease, and two patients (29%) in response to treatment. Overall, PET-CT induced a shift in the management of 10 patients (28%).
Our study and other publications suggest that PET-CT should be used in: initial staging in Stage III and IV; detection of recurrent disease; and evaluation of treatment response.
我们这项回顾性研究的目的是评估正电子发射断层显像-计算机断层扫描(PET-CT)在上消化道(UADT)鳞状细胞癌管理中的作用。
我们的研究纳入了43例接受PET-CT检查的UADT鳞状细胞癌患者,检查目的分别为:初始分期(n = 20)、复发性疾病诊断(n = 16)以及治疗反应评估(n = 7)。
在初始分期中,PET-CT诊断出4例(20%)常规影像学检查漏诊的远处转移;在复发性疾病诊断中,诊断出4例(25%);在治疗反应评估中,诊断出2例(29%)。总体而言,PET-CT导致10例(28%)患者的治疗方案发生改变。
我们的研究及其他文献表明,PET-CT应用于:Ⅲ期和Ⅳ期的初始分期;复发性疾病的检测;以及治疗反应的评估。