Frimodt-Møller Niels, Gahrn-Hansen Bente
Statens Serum Institut, Afdelingen for Antibiotikaresistens og Sygehushygiejne.
Ugeskr Laeger. 2007 Dec 3;169(49):4254-6.
Antibiotic consumption has increased by around 50% in Danish hospitals over the last 7 years. In percentages, the highest increase has been among broad spectrum antibiotics such as cephalosporins, crabapenems and fluoroquinolones. The consequence of this is selection of resistant bacteria and fungi. Control of antibiotic resistance requires implementation of different strategies: better and more rapid diagnosis of infectious origin, restriction on antibiotic use, e.g. through re-evaluation every 2-3 days of patients receiving antibiotics, optimization of dosing and duration of treatment, preferred use of narrow spectrum antibiotics and optimization of hospital hygiene.
在过去7年里，丹麦医院的抗生素使用量增加了约50%。按百分比计算，增幅最大的是广谱抗生素，如头孢菌素、碳青霉烯类和氟喹诺酮类。其后果是耐药细菌和真菌的产生。控制抗生素耐药性需要实施不同的策略：更好、更快速地诊断感染源，限制抗生素使用，例如通过每2 - 3天对接受抗生素治疗的患者进行重新评估，优化给药剂量和治疗时长，优先使用窄谱抗生素，以及优化医院卫生条件。
