滞留时间及其在药理学中的应用。
The sojourn time and its use in pharmacology.
作者信息
Segre G, Urso R
机构信息
Instituto di Farmacologia, Laboratorio di Farmacocinetica, Università di Siena, Italy.
出版信息
Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:501-6.
PMID:1820930
Abstract
A short review on some pharmacokinetic parameters (mean residence time, sojourn time, transit time) is given in relation to compartmental models and some examples and application are discussed. In particular the use of the sojourn time is suggested because this parameter can give useful informations when comparing the pharmacokinetics of different drugs or in pharmacodynamics.
摘要
本文给出了一些药代动力学参数（平均驻留时间、逗留时间、通过时间）与房室模型相关的简短综述，并讨论了一些实例和应用。特别建议使用逗留时间，因为在比较不同药物的药代动力学或药效学方面，该参数可提供有用信息。
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