[Anti-ulcerogenic action of a combination of a psychostimulator of the phenylalkylsydnone imine series and arginine].

It has been revealed that OF 743, one of the psychostimulators belonging to phenylalkylsydnonimine derivatives, exerts anti-ulcerogenic action in case of stress- and ethanol-induced damage of gastric mucosa in rats. However OF 743 was not effective in case of indomethacin-induced gastric mucosal damage. Complex administration of OF 743 and arginine was accompanied by a considerable decrease of indomethacin-induced gastric mucosal damage. That combination was more effective than OF 743 alone in case of ethanol-induced gastric mucosal damage.