Scott Katherine C, Philip Susan, Ahrens Katherine, Kent Charlotte K, Klausner Jeffrey D
San Francisco Department of Public Health Sexually Transmitted Disease Control and Prevention Services San Francisco, CA, USA.
J Acquir Immune Defic Syndr. 2008 May 1;48(1):109-12. doi: 10.1097/QAI.0b013e318165dc0b.
The increasing use of point-of-care HIV tests in sexually transmitted disease (STD) clinics allows for rapid identification of patients with newly diagnosed HIV infection who may also be at risk for more common sexually transmitted infections. Positive point-of-care HIV test results might be used to identify and provide presumptive treatment to patients who are likely to be coinfected with gonorrhea (GC) and chlamydia (CT).
Data from 6864 STD clinic visits by men who have sex with men (MSM) with no history of HIV infection and an HIV antibody test at that visit were analyzed. Results from rectal, pharyngeal, and urine nucleic acid amplification tests were used to calculate the prevalence of infection with GC and CT.
MSM with newly diagnosed HIV infection were more likely than HIV-uninfected MSM to be infected with GC (25.9% [53 of 205] vs. 10.9% [728 of 6659]; P < 0.001) and CT (18.5% [38 of 205] vs. 7.8% [518 of 6659]; P < 0.001).
GC and CT are common in MSM with newly diagnosed HIV infection at an STD clinic. In this population, a positive point-of-care HIV test result is a useful risk marker for untreated gonococcal and chlamydial infections and provides a justification for presumptive GC and CT treatment.
在性传播疾病（STD）诊所中，即时检验HIV的应用日益广泛，这使得能够快速识别新诊断出HIV感染的患者，这些患者可能同时面临更常见性传播感染的风险。即时检验HIV的阳性结果可用于识别那些可能同时感染淋病（GC）和衣原体（CT）的患者，并为其提供推定治疗。
分析了6864名无HIV感染史且在就诊时进行了HIV抗体检测的男男性行为者（MSM）的STD诊所就诊数据。直肠、咽部和尿液核酸扩增检测结果用于计算GC和CT的感染率。
新诊断出HIV感染的MSM比未感染HIV的MSM更易感染GC（25.9%[205例中的53例]对10.9%[6659例中的728例]；P<0.001）和CT（18.5%[205例中的38例]对7.8%[6659例中的518例]；P<0.001）。
在STD诊所新诊断出HIV感染的MSM中，GC和CT感染很常见。在这一人群中，即时检验HIV的阳性结果是未治疗的淋球菌和衣原体感染的有用风险标志物，为推定GC和CT治疗提供了依据。
