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[全氟烷注入兔眼前房和玻璃体的实验研究]

[Experimental studies of administration of perfluoroalkane to the anterior chamber and vitreous body of rabbits].

作者信息

Karczewicz D, Mozolewska K, Lubiński W, Lubiński J, Meissner E

机构信息

I i II Kliniki Okulistycznej AM w Szczecinie.

出版信息

Klin Oczna. 1991 Oct-Nov;93(10-11):278-80.

PMID:1821008
Abstract

Presented are the results of experimental investigations evaluating the influence of perfluoroalcane on the ocular tissue in rabbits. The examined animals were divided into 2 groups. The rabbits from the first one received the compound into the anterior chamber of the right eye, the rabbits from the 2-nd group to the vitreous of the right eye. The left eye was the control one. Evaluated was the degree of absorption of the compound from the anterior chamber and vitreous, its influence on the anterior segment, transparency of the lens and intraocular pressure. An ERG was performed before the application of the compound and after 7, 14 and 49 days; subsequently the eyes were excised and a histopathological examination was performed in a light microscope.

摘要

呈现的是评估全氟烷烃对兔眼组织影响的实验研究结果。所检查的动物被分为两组。第一组的兔子右眼前房接受该化合物,第二组的兔子右眼玻璃体接受该化合物。左眼作为对照。评估了该化合物从前房和玻璃体的吸收程度、其对眼前节、晶状体透明度和眼压的影响。在应用该化合物之前以及7天、14天和49天后进行了视网膜电图检查;随后切除眼睛并在光学显微镜下进行组织病理学检查。

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