Suppr超能文献

[关节置换成形术患者手术前后的金属敏感性]

[Metal sensitivity in patients with joint replacement arthroplasties before and after surgery].

作者信息

Rau C, Thomas P, Thomsen M

机构信息

Abteilung Orthopädie I, Orthopädische Universitätsklinik, Heidelberg, Deutschland.

出版信息

Orthopade. 2008 Feb;37(2):102-10. doi: 10.1007/s00132-007-1186-0.

Abstract

The object of the present study was to determine the incidence of metal sensitivity in patients with joint replacement arthroplasties before and after surgery and whether this is of significance as regards the final outcome of the operative procedure. A questionnaire-based survey involved 1,335 patients with an average age of 61 years and joint replacement arthroplasties before and after surgery. A history of dermal sensitivity to metal was given in 99 (7%) patients with almost equal frequency in the pre- and postoperative groups (7.6 vs 7.2%). In only 27 of 99 cases was the metal sensitivity recorded in the patient chart. In 46 cases investigation was done after knee or hip replacement arthroplasty with an average implant time in situ of 68 months. In 32 of 46 patients a sensitivity to the implanted material was known and they did not show any complications related to the metal sensitivity.It is currently unclear whether metal sensitivity could be induced by joint replacement arthroplasties and it remains uncertain whether loosening or infection causes the sensitization as a consequence of increased release of metal ions or vice versa. To draw further conclusions considerably more detailed studies involving more patients are clearly indicated.

摘要

本研究的目的是确定关节置换成形术患者手术前后金属过敏的发生率,以及这对于手术最终结果是否具有重要意义。一项基于问卷的调查涉及1335例平均年龄为61岁的关节置换成形术患者,涵盖手术前后。99例(7%)患者有对金属的皮肤过敏史,术前组和术后组的发生率几乎相同(7.6%对7.2%)。在99例病例中,仅有27例的金属过敏情况记录在患者病历中。46例患者在膝关节或髋关节置换成形术后接受了调查,植入物平均在位时间为68个月。在46例患者中的32例已知对植入材料过敏,但他们未表现出任何与金属过敏相关的并发症。目前尚不清楚关节置换成形术是否会诱发金属过敏,也不确定松动或感染是否由于金属离子释放增加而导致致敏,反之亦然。显然需要开展涉及更多患者的更为详细的研究才能得出进一步结论。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验