Dietrich Karin-Almut, Mazoochian Farhad, Summer Burkhard, Reinert Mark, Ruzicka Thomas, Thomas Peter
Department of Dermatology and Allergy, University of Munich, Germany.
J Dtsch Dermatol Ges. 2009 May;7(5):410-3. doi: 10.1111/j.1610-0387.2008.06987.x. Epub 2009 Jan 15.
Intolerance reactions to metal implants may present as dermatitis, impaired wound healing, effusions, pain or loosening. The clinical relevance of metal allergy in the differential diagnosis is often unclear and patients may even tolerate implants containing metals to which they are allergic. We present four patients with knee arthroplasty in whom after exclusion of infection or mechanical causes, a nickel/cobalt allergy led to replacement surgery with titanium-based prostheses. The subsequent alleviation of symptoms underlined the relevance and usefulness of allergological diagnostics in selected cases of complicated arthroplasty.
对金属植入物的不耐受反应可能表现为皮炎、伤口愈合受损、积液、疼痛或松动。金属过敏在鉴别诊断中的临床相关性往往不明确，患者甚至可能耐受含有他们过敏金属的植入物。我们介绍了四名接受膝关节置换术的患者，在排除感染或机械原因后，镍/钴过敏导致他们接受了钛基假体的置换手术。随后症状的缓解突出了变应性诊断在复杂关节置换术特定病例中的相关性和实用性。
