Babler W J
Department of Anatomy, Baylor College of Dentistry, Dallas, Texas.
Neurosurg Clin N Am. 1991 Jul;2(3):539-49.
In a series of experimental studies, the effects of induced premature closure of a normal cranial suture on the normal growth pattern of the rabbit skull are reported. In general, the results indicate that the craniofacial skeleton is an integrated growing unit in which alteration in growth of one component has profound effects on growth of other components. The magnitude and type of compensatory response depend on the type of suture, i.e., cranial or facial, its location, and timing of the growth insult. It is also important to note that the timing of surgical intervention has a direct effect on the capability of the growing craniofacial skeleton to obtain a more typical growth pattern.
在一系列实验研究中，报告了诱导正常颅骨缝线过早闭合对兔颅骨正常生长模式的影响。总体而言，结果表明颅面骨骼是一个综合生长单位，其中一个组成部分生长的改变会对其他组成部分的生长产生深远影响。代偿反应的程度和类型取决于缝线的类型，即颅骨或面部缝线、其位置以及生长损伤的时间。还需要注意的是，手术干预的时机对生长中的颅面骨骼获得更典型生长模式的能力有直接影响。
