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[皮肤保护的三步方案。是一级预防的有用工具还是在二级预防中更有效?]

[The three-step programme of skin protection. A useful instrument of primary prevention or more effective in secondary prevention?].

作者信息

Kütting B, Drexler H

机构信息

Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin der Friedrich-Alexander Universität Erlangen-Nürnberg, Schillerstr. 25 + 29, 91054 Erlangen.

出版信息

Dtsch Med Wochenschr. 2008 Feb;133(5):201-5. doi: 10.1055/s-2008-1017498.

Abstract

For many years the three-step programme of skin protection, consisting of skin protection before work, cleaning and skin care after work, is one of the generally recommended measures to prevent occupational contact dermatitis. While protective creams are supposed to prevent skin damage caused by irritant contact, skin cleansing should mildly remove aggressive substances from the skin, whereas post-exposure skin care is intended to enhance epidermal barrier regeneration. This programme is strongly followed by most of the employees. But in spite of intensive preventive measurements the rate of reported occupational skin diseases according to BK 5101 is with a mean of 27.9% unchanged high since 1980. Occupational dermatologists even suggest that the reported cases mimic the top of an iceberg and that the incidence of occupational skin diseases might be much higher. These findings raise the question of how effective the actual recommended three-step programme really is in primary and secondary prevention of occupational contact dermatitis. This review is aimed to give an evaluation on the evidence of each single element of the three-step concept. Following results can be determined: In cases of impaired skin condition the therapeutic properties of skin protection (secondary prevention) is undoubted. The effectiveness of barrier creams in the primary prevention of hand eczema could not be proven. Beyond doubt is the fact that barrier creams facilitate the removal of sticky oils, greases, and resins from the skin, thus decreasing the need to wash with potentially irritating abrasives and waterless cleansers.

摘要

多年来,由工作前皮肤防护、工作后清洁和皮肤护理组成的三步皮肤防护方案,是预防职业性接触性皮炎普遍推荐的措施之一。防护霜应能防止刺激性接触导致的皮肤损伤,皮肤清洁应温和地清除皮肤上的侵蚀性物质,而暴露后皮肤护理旨在促进表皮屏障再生。大多数员工都严格遵循这一方案。但尽管采取了密集的预防措施,自1980年以来,根据BK 5101报告的职业性皮肤病发病率平均仍高达27.9%,未见变化。职业皮肤科医生甚至认为,报告的病例只是冰山一角,职业性皮肤病的发病率可能要高得多。这些发现引发了一个问题,即实际推荐的三步方案在职业性接触性皮炎的一级和二级预防中到底有多有效。本综述旨在对三步概念中每个单一要素的证据进行评估。可以确定以下结果:在皮肤状况受损的情况下,皮肤防护(二级预防)的治疗特性是毋庸置疑的。防护霜在手部湿疹一级预防中的有效性尚未得到证实。毫无疑问的是,防护霜有助于清除皮肤上的粘性油、油脂和树脂,从而减少使用可能具有刺激性的研磨剂和无水清洁剂清洗的必要性。

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