首次使用低剂量西酞普兰相关的血清素综合征。

First time, low dose citalopram use-related serotonin syndrome.

作者信息

Turedi Suleyman, Eraydin Ismet, Gunduz Abdulkadir, Kalkan Asim, Hos Ulku

机构信息

Karadeniz Technical University, Faculty of Medicine, Department of Emergency Medicine, Trabzon, Turkey.

出版信息

Neurotoxicology. 2007 Nov;28(6):1272-4. doi: 10.1016/j.neuro.2007.05.004.

DOI:10.1016/j.neuro.2007.05.004

PMID:18213744

Abstract

Citalopram is a very potent and highly selective inhibitor of neuronal serotonin (5-hydroxytryptamine, or 5-HT). Serotonin syndrome is a rarely observed side-effect of Citalopram use. This report discusses a case of first time, low dose citalopram use-related serotonin syndrome presenting with confusion, hyperhidrosis, hyperreflexia, myoclonus and fever.

摘要

西酞普兰是一种强效且高度选择性的神经元5-羟色胺（5-羟色胺，或5-HT）抑制剂。血清素综合征是使用西酞普兰罕见的副作用。本报告讨论了一例首次使用低剂量西酞普兰相关的血清素综合征病例，表现为意识模糊、多汗、反射亢进、肌阵挛和发热。