Choudry Umar H, Bakri Karim, Moran Steven L, Karacor Zeynep, Shin Alexander Y
Mayo Clinic, Rochester, MN 55905, USA.
Ann Plast Surg. 2008 Feb;60(2):174-80. doi: 10.1097/SAP.0b013e318056d6b5.
The purpose of this study was to examine our experience with this flap for the treatment of recalcitrant nonunions of the extremities. A retrospective chart review was performed on 11 consecutive patients treated with the medial femoral periosteal bone flap from June 2003 to March 2005. Patient demographics, nonunion characteristics, complications, and long-term outcome based on radiographic and clinical parameters were analyzed. Nine free transfers and 3 pedicled flaps were used for a total of 12 nonunion sites in 11 patients. The average age of the patient population was 49 years (21-64 years). The location of the nonunion sites were femur (n = 4), tibia (n = 2), humerus (n = 3), clavicle (n = 2), and radius (n = 1). The nonunion sites were secondary to traumatic fractures complicated by osteomyelitis (n = 10) and tumor extirpation (n = 2). The time period of nonunion prior to the use of vascularized periosteal bone graft ranged from 10 months to 23 years (median = 23 months). All patients had previous attempts at debridement with or without antibiotic bead placement, and all underwent rigid fixation with or without nonvascularized bone grafts prior to vascularized grafting. Following flap placement, 9 (75%) of the nonunion sites healed primarily without complication at an average period of 3.8 months (2-7 months). Two nonunions healed secondarily following hardware modification. There was only 1 flap failure secondary to arterial thrombosis, resulting in a below-knee amputation. The rate of limb salvage was 91%. Donor-site morbidity was minimal, with postoperative seromas occurring in 3 patients.
本研究的目的是探讨我们使用该皮瓣治疗四肢顽固性骨不连的经验。对2003年6月至2005年3月期间连续接受股内侧骨膜骨皮瓣治疗的11例患者进行了回顾性病历审查。分析了患者的人口统计学资料、骨不连特征、并发症以及基于影像学和临床参数的长期预后。共对11例患者的12个骨不连部位使用了9例游离移植和3例带蒂皮瓣。患者的平均年龄为49岁(21 - 64岁)。骨不连部位位于股骨(n = 4)、胫骨(n = 2)、肱骨(n = 3)、锁骨(n = 2)和桡骨(n = 1)。骨不连部位继发于创伤性骨折合并骨髓炎(n = 10)和肿瘤切除(n = 2)。在使用带血管蒂骨膜骨移植之前,骨不连的时间范围为10个月至23年(中位数 = 23个月)。所有患者之前均尝试过清创,有或没有放置抗生素珠,并且在进行带血管蒂移植之前均接受了有或没有非血管化骨移植的坚强内固定。皮瓣植入后,9个(75%)骨不连部位一期愈合,无并发症,平均愈合时间为3.8个月(2 - 7个月)。2个骨不连部位在进行硬件修改后二期愈合。仅1例皮瓣因动脉血栓形成失败,导致膝下截肢。保肢率为91%。供区并发症极少,3例患者术后出现血清肿。