El Amm Christian A, Denny Arlen
Department of Surgery, Section of Plastic Surgery, University of Oklahoma, 920 S.L. Young Boulevard, Oklahoma City, OK 73104, USA.
J Craniofac Surg. 2008 Jan;19(1):259-63. doi: 10.1097/scs.0b013e31815c9460.
Hyoid bone abnormalities have not been previously documented in association with Pierre Robin Sequence. Using three-dimensional (3D) reconstructions of helical computed tomography scans, we examined the hyoid bones of neonates affected with Pierre Robin Sequence and compared them to helical scans of unaffected controls. Severe hyoid bone abnormalities were observed in 7/28 cases, and mild abnormalities in another 16. The presence of severe abnormalities was significantly associated with swallowing dysfunction, while none of the neonates affected with Stickler's syndrome were observed to have severe hyoid abnormalities. The significance of these findings is unknown. Clinicians should be aware of these abnormalities because of the wide availability of 3D reformats.
舌骨异常此前尚未被记载与皮埃尔·罗宾序列征相关。我们利用螺旋计算机断层扫描的三维（3D）重建技术，检查了患有皮埃尔·罗宾序列征的新生儿的舌骨，并将其与未受影响的对照组的螺旋扫描结果进行比较。在28例病例中有7例观察到严重舌骨异常，另有16例有轻度异常。严重异常的存在与吞咽功能障碍显著相关，而未观察到患有斯蒂克勒综合征的新生儿有严重舌骨异常。这些发现的意义尚不清楚。由于3D重建技术的广泛应用，临床医生应了解这些异常情况。
