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无易感风险因素患者的原发性胸锁关节化脓性关节炎。

Primary sternoclavicular septic arthritis in patients without predisposing risk factors.

作者信息

Gallucci F, Esposito P, Carnovale A, Madrid E, Russo R, Uomo G

机构信息

Department of Internal Medicine, Cardarelli Hospital, Napoli, Italy.

出版信息

Adv Med Sci. 2007;52:125-8.

Abstract

BACKGROUND

Septic arthritis (SA) of the sternoclavicular joint (SCJ) is an uncommon form of arthritis, generally described in patients with predisposing risk factors such as primary or secondary immunosuppressive disorders, systemic or localized infections and central venous catheters. More rarely the infection occurs in patients without these risk factors, thus rendering difficult an early diagnosis.

MATERIAL AND METHODS

We report two cases of SA of the SCJ occurred in two patient, without known predisposing risk factors, hospitalized in our Internal Medicine Unit.

RESULTS

The clinical characteristics didn't significantly differ from clinical course of the disease occurring in patients with predisposing risk factors. Imaging techniques were useful to suspect diagnosis, but only fine-needle aspiration biopsy with culture of specimens leaded to identify the pathogen and its antibiotic sensitivity (in both patients Staphylococcus aureus). One patient was treated with surgical adequate curettage, drainage and intravenous methicillin, while the other one received only medical treatment with intravenous teicoplanin and ceftazidime. The outcome was uneventful with a complete recovery in both cases.

CONCLUSIONS

Even if SA of SCJ is uncommon in subjects without predisposing risk factors, the clinician must have a high index of suspicion to consider this disease in differential diagnosis of arthritis also in previously healthy subjects with negative or unsettling instrumental investigations. In fact, prompt diagnosis is essential to obtain a successful outcome, avoiding the prolongation of the hospitalization and the sequelae of a chronic infection.

摘要

背景

胸锁关节(SCJ)化脓性关节炎(SA)是一种罕见的关节炎形式,通常见于具有易感危险因素的患者,如原发性或继发性免疫抑制性疾病、全身性或局部感染以及中心静脉导管。更罕见的是,感染发生在没有这些危险因素的患者中,因此早期诊断较为困难。

材料与方法

我们报告了两例SCJ的SA病例,发生在两名患者身上,他们没有已知的易感危险因素,在我们内科病房住院。

结果

临床特征与有易感危险因素患者所患疾病的临床病程无显著差异。影像学技术有助于怀疑诊断,但只有通过细针穿刺活检并对标本进行培养才能确定病原体及其抗生素敏感性(两名患者均为金黄色葡萄球菌)。一名患者接受了手术充分刮除、引流及静脉注射甲氧西林治疗,而另一名患者仅接受了静脉注射替考拉宁和头孢他啶的药物治疗。两例患者均顺利康复,完全恢复。

结论

即使SCJ的SA在没有易感危险因素的患者中不常见,但临床医生在对既往健康但检查结果为阴性或不确定的关节炎患者进行鉴别诊断时,也必须高度怀疑这种疾病。事实上,及时诊断对于取得成功的治疗结果至关重要,可避免住院时间延长及慢性感染的后遗症。

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